B
Brian Tung
Researcher at Harvard University
Publications - 19
Citations - 521
Brian Tung is an academic researcher from Harvard University. The author has contributed to research in topics: Mace & Population. The author has an hindex of 8, co-authored 18 publications receiving 300 citations. Previous affiliations of Brian Tung include Beth Israel Deaconess Medical Center & New York Medical College.
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Journal ArticleDOI
Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation
TL;DR: It is demonstrated that tumor cells with decreased TNC expression are sensitive to anti-proliferative treatment in vitro and in vivo, and detailed understanding of how TNC in the tumor microenvironment influences tumor behavior and the interactions between tumor cells and surrounding nontumor cells will benefit novel combinatory antitumor strategies to treat malignant brain tumors.
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Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease.
Ahmed Tawakol,Michael T. Osborne,Ying Wang,Basma Hammed,Brian Tung,Tomas Patrich,Blake Oberfeld,Amorina Ishai,Lisa M. Shin,Matthias Nahrendorf,Erica T. Warner,Jason H. Wasfy,Zahi A. Fayad,Karestan C. Koenen,Paul M. Ridker,Roger K. Pitman,Katrina Armstrong +16 more
TL;DR: A stress-associated neurobiological mechanism by which SES disparities may potentiate adverse health outcomes is illuminated by a serial pathway that includes higher amygdalar activity, bone marrow activity, and arterial inflammation.
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Imaging Cardiovascular Calcification.
TL;DR: Current imaging techniques for vascular calcification are summarized and their applications in clinical research are summarized to help identify individuals with enhanced risk of cardiovascular events.
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A neurobiological mechanism linking transportation noise to cardiovascular disease in humans
Michael T. Osborne,Azar Radfar,Malek Z.O. Hassan,Shady Abohashem,Blake Oberfeld,Tomas Patrich,Brian Tung,Ying Wang,Ying Wang,Amorina Ishai,James A. Scott,Lisa M. Shin,Lisa M. Shin,Zahi A. Fayad,Karestan C. Koenen,Sanjay Rajagopalan,Roger K. Pitman,Ahmed Tawakol +17 more
TL;DR: Noise exposure associates with MACE via a mechanism that begins with increased stress-associated limbic activity and includes heightened arterial inflammation, a potential neurobiological mechanism linking noise to CVD merits further evaluation in a prospective population.
Journal ArticleDOI
Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration.
Jun Wan,Yijing Su,Qifeng Song,Brian Tung,Brian Tung,Olutobi Oyinlade,Sheng Liu,Mingyao Ying,Mingyao Ying,Guo Li Ming,Hongjun Song,Jiang Qian,Heng Zhu,Shuli Xia +13 more
TL;DR: The biological function of mCpG-dependent gene regulation by KLF4 in glioblastoma cells is reported, demonstrating a new paradigm of DNA methylation-mediated gene activation and chromatin remodeling, and providing a general framework to dissect the biological functions ofDNA methylation readers and effectors.