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Brian W. Whitcomb
Researcher at University of Massachusetts Amherst
Publications - 170
Citations - 6336
Brian W. Whitcomb is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Population & Pregnancy. The author has an hindex of 38, co-authored 147 publications receiving 5016 citations. Previous affiliations of Brian W. Whitcomb include University of Maryland, Baltimore & National Institutes of Health.
Papers
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Youden Index and optimal cut-point estimated from observations affected by a lower limit of detection.
TL;DR: The limitations and usefulness of each method are addressed in order to give researchers guidance in constructing appropriate estimates of biomarkers' true discriminating capabilities.
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Lipid adjustment in the analysis of environmental contaminants and human health risks
TL;DR: It is concluded that investigators must consider biology, biologic medium, laboratory measurement, and other underlying modeling assumptions when devising a statistical plan for assessing health outcomes in relation to environmental exposures.
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The Limitations due to Exposure Detection Limits for Regression Models
TL;DR: The authors propose distribution-free methods for managing values below detection limits and evaluate the biases that may result when exposure measurement is constrained by a lower threshold to inform decisions regarding analytical plans for future studies.
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Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations.
Brian W. Whitcomb,Elizabeth Kimbrough Pradhan,Anastassios G. Pittas,Mary-Claire Roghmann,Eli N. Perencevich +4 more
TL;DR: The association between hyperglycemia on intensive care unit admission and in-hospital mortality was not uniform in the study population; hyperglyCEmia was an independent risk factor only in patients without diabetic history in the cardiac, cardiothoracic, and neurosurgical intensive care units.
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The metabolic syndrome, diabetes, and subclinical atherosclerosis assessed by coronary calcium.
Nathan D. Wong,Maria G. Sciammarella,Donna M. Polk,Amy M. Gallagher,Lisa Miranda-Peats,Brian W. Whitcomb,Rory Hachamovitch,John D. Friedman,Sean W. Hayes,Daniel S. Berman +9 more
TL;DR: Those with MetS or diabetes have an increased likelihood of CAC compared with those having neither condition and by number of MetS risk factors were determined.