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Brigitte Le Mauff
Researcher at University of Caen Lower Normandy
Publications - 12
Citations - 336
Brigitte Le Mauff is an academic researcher from University of Caen Lower Normandy. The author has contributed to research in topics: Antigen-presenting cell & Interleukin 21. The author has an hindex of 5, co-authored 12 publications receiving 244 citations.
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Journal ArticleDOI
Long-Term Remissions of Severe Pemphigus After Rituximab Therapy Are Associated with Prolonged Failure of Desmoglein B Cell Response
Natacha Colliou,Damien Picard,Frédérique Caillot,Sébastien Calbo,Stéphanie Le Corre,Annick Lim,Brigitte Lemercier,Brigitte Le Mauff,Maud Maho-Vaillant,Serge Jacquot,Christophe Bedane,Philippe Bernard,Frédéric Caux,Catherine Prost,Emmanuel Delaporte,Marie-Sylvie Doutre,Brigitte Dréno,Nathalie Franck,Saskia Ingen-Housz-Oro,Olivier Chosidow,Christine Pauwels,Catherine Picard,Jean-Claude Roujeau,M.-L. Sigal,E. Tancrede-Bohin,Isabelle Templier,Rüdiger Eming,Michael Hertl,Michel D'Incan,Pascal Joly,Philippe Musette +30 more
TL;DR: It is found that rituximab therapy can help pemphigus patients even after 6 years, in part by reshaping the B cell repertoire during reconstitution, allowing for long-term effects in addition to the short-term loss of pathogenic B cells.
Journal ArticleDOI
B‐cell subpopulations in children: National reference values
Marie Duchamp,Delphine Sterlin,Aminata Diabate,Béatrice Uring-Lambert,Valérie Guérin-El Khourouj,Brigitte Le Mauff,Delphine Monnier,Christophe Malcus,Myriam Labalette,Capucine Picard +9 more
TL;DR: It was found that the naive B‐cells percentage declined between the ages of 6 months and 8 years, after which it remained stable at about 70–80%, and the definition of reference intervals for pediatric B‐cell levels should facilitate the screening and diagnosis of various B‐ cell immunodeficiencies.
Journal ArticleDOI
Rhupus: a systematic literature review
TL;DR: A systematic literature review is presented to analyze the clinical and laboratory data of all reported rhupus patients and to provide up-to-date information about recent advances in the understanding of the pathophysiological mechanisms, diagnostic tools and treatment options.
Journal ArticleDOI
Increased frequencies of circulating and tumor-resident Vδ1+ T cells in patients with diffuse large B-cell lymphoma.
Emilie Reboursiere,Anne-Claire Gac,Anthony Garnier,Véronique Salaun,Oumedaly Reman,Anne-Dominique Pham,Quentin Cabrera,Kathy Khoy,Jean-Pierre Vilque,Christophe Fruchart,Sylvain Chantepie,Hyacinthe Johnson-Ansah,Margaret Macro,Stéphane Cheze,Khaled Benabed,Jean-Baptiste Mear,Xavier Troussard,Gandhi Damaj,Brigitte Le Mauff,Olivier Toutirais +19 more
TL;DR: Interestingly, the germinal center (GC) subtype was associated with an increase in Vδ1+ T cells in tumors, whereas the non-GC subtypewas associated with a lower frequency of γδ T cells.
Journal ArticleDOI
Risk factors associated with hypersensitivity reactions to cetuximab: anti-cetuximab IgE detection as screening test
Benoît Dupont,Delphine Mariotte,Bénédicte Clarisse,Marie-Pierre Galais,Karine Bouhier-Leporrier,Jean-Michel Grellard,Brigitte Le Mauff,Jean-Marie Reimund,Radj Gervais +8 more
TL;DR: Anti-cetuximab IgE may help physicians identify patients at risk of a hypersensitivity reaction to cetuxIMab.