B
Brisa Palikuqi
Researcher at Cornell University
Publications - 14
Citations - 900
Brisa Palikuqi is an academic researcher from Cornell University. The author has contributed to research in topics: Endothelial stem cell & Regeneration (biology). The author has an hindex of 6, co-authored 11 publications receiving 635 citations. Previous affiliations of Brisa Palikuqi include Howard Hughes Medical Institute & Harvard University.
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Journal ArticleDOI
Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration
Daniel J. Nolan,Michael Ginsberg,Edo Israely,Brisa Palikuqi,Michael G. Poulos,Daylon James,Bi-Sen Ding,William Schachterle,Ying Liu,Zev Rosenwaks,Jason M. Butler,Jenny Xiang,Arash Rafii,Arash Rafii,Koji Shido,Sina Y. Rabbany,Sina Y. Rabbany,Olivier Elemento,Shahin Rafii +18 more
TL;DR: It is shown that clusters of transcription factors, angiocrine growth factors, adhesion molecules, and chemokines are expressed in unique combinations by ECs of each organ.
Journal ArticleDOI
Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
Brisa Palikuqi,Duc-Huy T. Nguyen,Ge Li,Ryan Schreiner,Alessandro Filippo Pellegata,Ying Liu,David Redmond,Fuqiang Geng,Yang Lin,Jesus M. Gomez-Salinero,Masataka Yokoyama,Paul Zumbo,Tuo Zhang,Balvir Kunar,Mavee Witherspoon,Teng Han,Alfonso M Tedeschi,Federico Scottoni,Steven M. Lipkin,Lukas E. Dow,Olivier Elemento,Jenny Xiang,Koji Shido,Jason R. Spence,Qiao Zhou,Robert E. Schwartz,Paolo De Coppi,Paolo De Coppi,Sina Y. Rabbany,Sina Y. Rabbany,Shahin Rafii +30 more
TL;DR: The transient reactivation of ETV2 in adult human endothelial cells reprograms these cells to become adaptable vasculogenic endothelia that in three-dimensional matrices self-assemble into vascular networks that can transport blood and physiologically arborize organoids and decellularized tissues.
Journal ArticleDOI
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
Tobias Wertheimer,Enrico Velardi,Jennifer Tsai,Jennifer Tsai,Kirsten Cooper,Shiyun Xiao,Christopher C. Kloss,Christopher C. Kloss,Katja J. Ottmüller,Zeinab Mokhtari,Christian Brede,Paul DeRoos,Sinéad Kinsella,Brisa Palikuqi,Michael Ginsberg,Lauren F. Young,Fabiana M Kreines,Sophia R. Lieberman,Amina Lazrak,Peipei Guo,Florent Malard,Odette M. Smith,Yusuke Shono,Robert R. Jenq,Alan M. Hanash,Daniel J. Nolan,Jason M. Butler,Andreas Beilhack,Nancy R. Manley,Shahin Rafii,Jarrod A Dudakov,Jarrod A Dudakov,Marcel R.M. van den Brink +32 more
TL;DR: Thymic endothelial cells comprise a critical pathway of regeneration via their production of bone morphogenetic protein 4 (BMP4), demonstrating the importance of the BMP4 pathway in endogenous tissue regeneration and offering a potential clinical approach to enhance T cell immunity.
Journal ArticleDOI
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression
Peipei Guo,Michael G. Poulos,Brisa Palikuqi,Chaitanya R. Badwe,Raphael Lis,Balvir Kunar,Bi-Sen Ding,Sina Y. Rabbany,Sina Y. Rabbany,Koji Shido,Jason M. Butler,Shahin Rafii +11 more
TL;DR: It is shown that under steady state, jagged-2 is differentially expressed in tissue-specific vascular beds, but its expression is induced in hematopoietic vascular niches after myelosuppressive injury.
Journal ArticleDOI
Novel Biopanning Strategy To Identify Epitopes Associated with Vaccine Protection
Barbara C. Bachler,Barbara C. Bachler,Michael Humbert,Brisa Palikuqi,Nagadenahalli B. Siddappa,Samir K. Lakhashe,Robert A. Rasmussen,Ruth M. Ruprecht +7 more
TL;DR: A novel, universally applicable strategy to profile the antibody (Ab) repertoire of protected vaccine recipients, using recombinant phages encoding random peptide libraries, suggests that Tat should be included in multicomponent HIV-1 vaccines.