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Bruce Mosley
Publications - 2
Citations - 1742
Bruce Mosley is an academic researcher. The author has contributed to research in topics: Translation (biology) & Peptide sequence. The author has an hindex of 2, co-authored 2 publications receiving 1720 citations.
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Journal ArticleDOI
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
Carl J. March,Bruce Mosley,Larsen Alf D,Douglas P. Cerretti,Gary Braedt,Virginia L. Price,Steven Gillis,Christopher S. Henney,Shirley R. Kronheim,Kenneth H. Grabstein,Paul J. Conlon,Thomas P. Hopp,David Cosman +12 more
TL;DR: Two distinct but distantly related complementary DNAs encoding proteins sharing human interleukin-1 (IL-1) activity (termed IL-lα and IL-1β), were isolated from a macrophage cDNA library.
Journal ArticleDOI
Determination of the minimum polypeptide lengths of the functionally active sites of human interleukins 1 alpha and 1 beta.
TL;DR: The localization of the biologically active portions within the initial polypeptide translation products is reported here and it is demonstrated that core sequences of amino acids for IL-1 beta and 140 amino acidsForIL-1 alpha must be left intact to retain full biological activity and further that the biological activities of the IL-2 polypeptic parallel their receptor binding capabilities.