G
Gary Braedt
Researcher at Virginia Mason Medical Center
Publications - 3
Citations - 2329
Gary Braedt is an academic researcher from Virginia Mason Medical Center. The author has contributed to research in topics: Peptide sequence & Amino acid. The author has an hindex of 3, co-authored 3 publications receiving 2298 citations.
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Journal ArticleDOI
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
Carl J. March,Bruce Mosley,Larsen Alf D,Douglas P. Cerretti,Gary Braedt,Virginia L. Price,Steven Gillis,Christopher S. Henney,Shirley R. Kronheim,Kenneth H. Grabstein,Paul J. Conlon,Thomas P. Hopp,David Cosman +12 more
TL;DR: Two distinct but distantly related complementary DNAs encoding proteins sharing human interleukin-1 (IL-1) activity (termed IL-lα and IL-1β), were isolated from a macrophage cDNA library.
Journal ArticleDOI
Localization of an ataxia-telangiectasia gene to chromosome 11q22–23
Richard A. Gatti,Izzet Berkel,Elena Boder,Gary Braedt,Patrick Charmley,Patrick Concannon,Fügen Ersoy,Tatiana Foroud,Nicholas G. J. Jaspers,Kenneth Lange,G. Mark Lathrop,Mark Leppert,Yusuke Nakamura,Peter O'Connell,Malcolm C. Paterson,Winston Salser,O. Sanal,O. Sanal,Jack Silver,Robert S. Sparkes,Ellen Susi,Daniel E. Weeks,Shan Wei,Ray White,Freda Yoder +24 more
TL;DR: It is suggested that as many as one in five women with breast cancer may carry the AT gene and that the increased radiation sensitivity of AT heterozygotes may be causing radiation therapists to reduce the doses of radiation used for treating cancer in all patients.
Journal ArticleDOI
Expression and Purification of Native Human Granulocyte-Macrophage Colony-Stimulating Factor from an Escherichia coli Secretion Vector
Randell T. Libby,Gary Braedt,Shirley R. Kronheim,Carl J. March,David L. Urdal,Teresa A. Chiaverotti,Robert J. Tushinski,Diane Y. Mochizuki,Thomas P. Hopp,David J. Cosman +9 more
TL;DR: Both versions of GM-CSF were associated with the membrane fraction after osmotic shock, and were purified to homogeneity by DEAE-Sephacel chromatography, followed by reversed-phase HPLC, establishing that the ompA signal peptide was cleaved at its normal processing site in both cases.