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Bruce W. Turnbull
Researcher at Cornell University
Publications - 125
Citations - 13178
Bruce W. Turnbull is an academic researcher from Cornell University. The author has contributed to research in topics: Sample size determination & Cancer. The author has an hindex of 42, co-authored 125 publications receiving 12726 citations. Previous affiliations of Bruce W. Turnbull include Durham University & University of Oxford.
Papers
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Journal ArticleDOI
Effects of Selenium Supplementation for Cancer Prevention in Patients With Carcinoma of the Skin: A Randomized Controlled Trial
Larry C. Clark,Gerald F. Combs,Bruce W. Turnbull,Elizabeth H. Slate,Dan K. Chalker,James Chow,Loretta S. Davis,Renee A. Glover,Gloria F. Graham,Earl G. Gross,Arnon Krongrad,Jack L. Lesher,H. Kim Park,Beverly B. Sanders,Cameron L. Smith,J. Richard Taylor +15 more
TL;DR: Results from secondary end-point analyses support the hypothesis that supplemental selenium may reduce the incidence of, and mortality from, carcinomas of several sites and require confirmation in an independent trial of appropriate design before new public health recommendations regarding seenium supplementation can be made.
Journal ArticleDOI
The Empirical Distribution Function with Arbitrarily Grouped, Censored, and Truncated Data
TL;DR: In this paper, a simple algorithm is constructed and shown to converge monotonically to yield a maximum likelihood estimate of a distribution function when the data are incomplete due to grouping, censoring and/or truncation.
Book
Group Sequential Methods with Applications to Clinical Trials
TL;DR: A short history of sequential and group sequential methods can be found in this paper, where the authors present a road map for the application of two-sided tests for comparing two treatments with normal response of known variance.
Journal ArticleDOI
Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial.
Larry C. Clark,Bruce L. Dalkin,Arnon Krongrad,Gerald F. Combs,Bruce W. Turnbull,Elizabeth H. Slate,Roy Witherington,J. H. Herlong,E. Janosko,D. Carpenter,C. Borosso,S. Falk,J. Rounder +12 more
TL;DR: Although selenium shows no protective effects against the primary endpoint of squamous and basal cell carcinomas of the skin, the selenum-treated group had substantial reductions in the incidence of prostate cancer, and total cancer incidence and mortality that demand further evaluation in well-controlled prevention trials.
Journal Article
Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: a summary report of the Nutritional Prevention of Cancer Trial.
Anna J. Duffield-Lillico,Mary E. Reid,Bruce W. Turnbull,Gerald F. Combs,Elizabeth H. Slate,Lori A. Fischbach,James R. Marshall,Larry C. Clark +7 more
TL;DR: The Nutritional Prevention of Cancer trial continues to show a protective effect of selenium on cancer incidence, although not all site-specific cancers exhibited a reduction in incidence.