C
C. Roux
Researcher at Paris Descartes University
Publications - 91
Citations - 3657
C. Roux is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Osteoporosis & Bone mineral. The author has an hindex of 31, co-authored 87 publications receiving 3292 citations.
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Journal ArticleDOI
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.
Emma L. Duncan,Patrick Danoy,John P. Kemp,Paul Leo,Eugene V. McCloskey,G.C. Nicholson,R. Eastell,Richard L. Prince,John A. Eisman,John A. Eisman,Graeme Jones,P. N. Sambrook,Ian R. Reid,Elaine M. Dennison,John D. Wark,J. B. Richards,J. B. Richards,André G. Uitterlinden,Tim D. Spector,Christopher T. Esapa,Christopher T. Esapa,Roger D. Cox,Steve D.M. Brown,Rajesh V. Thakker,K. Addison,Linda A. Bradbury,Cyrus Cooper,Cyrus Cooper,C. Cremin,Karol Estrada,Dieter Felsenberg,Claus-Christian Glüer,Johanna Hadler,Margaret J. Henry,Albert Hofman,Mark A. Kotowicz,Joanna Makovey,S.C. Nguyen,S.C. Nguyen,Tuan V. Nguyen,Tuan V. Nguyen,Julie A. Pasco,K. Pryce,David M. Reid,Fernando Rivadeneira,C. Roux,Kari Stefansson,Kari Stefansson,Unnur Styrkarsdottir,Gudmar Thorleifsson,R. Tichawangana,David M. Evans,Matthew A. Brown,Matthew A. Brown +53 more
TL;DR: This study confirms the efficiency of extreme-truncate selection designs for quantitative trait association studies in genome-wide association studies of BMD and identifies further genes associated with BMD.
Journal ArticleDOI
The effect of 8 or 5 years of denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM Extension study
S. Papapoulos,Kurt Lippuner,C. Roux,C J F Lin,David L. Kendler,E. M. Lewiecki,M. L. Brandi,Edward Czerwiński,Edward Franek,Peter L. Lakatos,Carlos Mautalen,Salvatore Minisola,Jean-Yves Reginster,S Jensen,Nadia Daizadeh,A. Wang,M Gavin,Cesar Libanati,Rachel B. Wagman,Henry G. Bone +19 more
TL;DR: Denosumab treatment for up to 8 years was associated with persistent reduction of bone turnover, continued increases in bone mineral density, low fracture incidence, and a favorable benefit/risk profile.
Journal Article
Osteoporosis, body composition, and bone turnover in ankylosing spondylitis.
TL;DR: Patients with AS are more susceptible to develop osteoporosis when they have low BMI, low fat mass percentage, and active and severe disease.
Journal ArticleDOI
Osteoporosis in inflammatory joint diseases
TL;DR: In this article, the optimal control of inflammation in RA is associated with decrease in structural damage and bone loss, and the role of inflammation on bone resorption is shown to be related mainly to inflammation.
Journal ArticleDOI
Imminent fracture risk
C. Roux,Karine Briot +1 more
TL;DR: Patients with an imminent (i.e. 2 years) risk of fracture or refracture should be identified in priority in order to receive an immediate treatment and a program of fall prevention.