Cari Graff-Cherry

TL;DR: Comparisons of gene expression patterns of endothelial cells derived from the blood vessels of eight normal resting tissues, five tumors, and regenerating liver reveal striking differences between physiological and pathological angiogenesis potentially important for the development of tumor-specific, vascular-targeted therapies.

TL;DR: Ex expression profiling is used to show that activated neonatal skin melanocytes isolated following a melanomagenic UVB dose bear a distinct, persistent interferon response signature, including genes associated with immunoevasion, identifying a novel candidate therapeutic target for a subset of melanoma patients.

TL;DR: Data is presented that demonstrates for the first time significant sunscreen prevention in UV-dependent, melanoma-prone transgenic mice, and proposes that when applied properly, sunscreen use should be preventive in people.

TL;DR: Ectopic expression of Mitf-M during development ofMitf-deficient mice is capable of partially rescuing ocular and retinal structures and uveal melanocytes and provides novel information about the roles of Mit f isoforms in the development of mouse eyes.