C
Caroline Dubuquoy
Researcher at French Institute of Health and Medical Research
Publications - 23
Citations - 1791
Caroline Dubuquoy is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Inflammation & Fibrosis. The author has an hindex of 11, co-authored 20 publications receiving 1574 citations. Previous affiliations of Caroline Dubuquoy include university of lille & Lille University of Science and Technology.
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Journal ArticleDOI
Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors.
Christel Rousseaux,Xavier Thuru,Xavier Thuru,Agathe Gelot,Nicolas Barnich,Christel Neut,Christel Neut,Laurent Dubuquoy,Laurent Dubuquoy,Caroline Dubuquoy,Caroline Dubuquoy,Emilie Mérour,Emilie Mérour,Karen Geboes,Mathias Chamaillard,Mathias Chamaillard,Arthur C. Ouwehand,Greg Leyer,Didier Carcano,Jean-Frederic Colombel,Jean-Frederic Colombel,Denis Ardid,Pierre Desreumaux,Pierre Desreumaux +23 more
TL;DR: It is found that oral administration of specific Lactobacillus strains induced the expression of μ-opioid and cannabinoid receptors in intestinal epithelial cells, and mediated analgesic functions in the gut—similar to the effects of morphine.
Rousseaux C, Thuru X, Gelot A, et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Christel Rousseaux,Xavier Thuru,Agathe Gelot,Nicolas Barnich,Christel Neut,Laurent Dubuquoy,Caroline Dubuquoy,Emilie Mérour,Karen Geboes,Mathias Chamaillard,Arthur C. Ouwehand,Greg Leyer,Didier Carcano,Jean-Frederic Colombel,Denis Ardid,Pierre Desreumaux +15 more
TL;DR: The authors found that oral administration of specific Lactobacillus strains induced the expression of μ-opioid and cannabinoid receptors in intestinal epithelial cells, and mediated analgesic functions in the gut.
Journal ArticleDOI
Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's disease
Laurent Peyrin-Biroulet,Florent Gonzalez,Laurent Dubuquoy,Christel Rousseaux,Caroline Dubuquoy,Cecilia Decourcelle,Alain Saudemont,Mickael Tachon,Elodie Beclin,Marie-Françoise Odou,Christel Neut,Jean-Frederic Colombel,Pierre Desreumaux +12 more
TL;DR: Mesenteric fat is an important source of CRP in Crohn's disease and production by mesenteric adipocytes may be triggered by local inflammation and bacterial translocation to mesEnteric fat, providing a mechanism whereby mesenteri fat hyperplasia may contribute to inflammatory response in CD.
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Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration.
Noura El-Jamal,Edmone Erdual,Michel Neunlist,Dine Koriche,Caroline Dubuquoy,François Maggiotto,Julien Chevalier,Dominique Berrebi,Laurent Dubuquoy,Eric Boulanger,Antoine Cortot,Pierre Desreumaux,Pierre Desreumaux +12 more
TL;DR: The limited therapeutic effect of GLP-2 on colonic inflammation dampens its utility in the management of severe inflammatory intestinal disorders and emphasizes on the importance of elucidating other extraintestinal functions of GLp-2.
Journal ArticleDOI
The schistosome glutathione S-transferase P28GST, a unique helminth protein, prevents intestinal inflammation in experimental colitis through a Th2-type response with mucosal eosinophils.
Virginie Driss,M El Nady,M El Nady,Marie Delbeke,Christel Rousseaux,Caroline Dubuquoy,Aurore Sarazin,S. Gatault,Arnaud Dendooven,Gilles Riveau,J-F Colombel,Pierre Desreumaux,Laurent Dubuquoy,Monique Capron +13 more
TL;DR: It is revealed that immunization with P28GST, a unique recombinant schistosome enzyme, ameliorates intestinal inflammation through eosinophil-dependent modulation of harmful type 1 responses, representing a new immuno-regulatory strategy against inflammatory bowel diseases.