D
Denis Ardid
Researcher at University of Auvergne
Publications - 81
Citations - 4958
Denis Ardid is an academic researcher from University of Auvergne. The author has contributed to research in topics: Neuropathic pain & Irritable bowel syndrome. The author has an hindex of 32, co-authored 79 publications receiving 4404 citations. Previous affiliations of Denis Ardid include French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors.
Christel Rousseaux,Xavier Thuru,Xavier Thuru,Agathe Gelot,Nicolas Barnich,Christel Neut,Christel Neut,Laurent Dubuquoy,Laurent Dubuquoy,Caroline Dubuquoy,Caroline Dubuquoy,Emilie Mérour,Emilie Mérour,Karen Geboes,Mathias Chamaillard,Mathias Chamaillard,Arthur C. Ouwehand,Greg Leyer,Didier Carcano,Jean-Frederic Colombel,Jean-Frederic Colombel,Denis Ardid,Pierre Desreumaux,Pierre Desreumaux +23 more
TL;DR: It is found that oral administration of specific Lactobacillus strains induced the expression of μ-opioid and cannabinoid receptors in intestinal epithelial cells, and mediated analgesic functions in the gut—similar to the effects of morphine.
Rousseaux C, Thuru X, Gelot A, et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Christel Rousseaux,Xavier Thuru,Agathe Gelot,Nicolas Barnich,Christel Neut,Laurent Dubuquoy,Caroline Dubuquoy,Emilie Mérour,Karen Geboes,Mathias Chamaillard,Arthur C. Ouwehand,Greg Leyer,Didier Carcano,Jean-Frederic Colombel,Denis Ardid,Pierre Desreumaux +15 more
TL;DR: The authors found that oral administration of specific Lactobacillus strains induced the expression of μ-opioid and cannabinoid receptors in intestinal epithelial cells, and mediated analgesic functions in the gut.
Journal ArticleDOI
Antidepressants and pain
TL;DR: In this paper, Tricyclic antidepressants are considered to be first-line drugs for the treatment of neuropathic pain, and they are shown to be analgesic in patients with chronic pain and no concomitant depression.
Journal ArticleDOI
Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome.
Christophe Chassard,Michel Dapoigny,Karen P. Scott,L. Crouzet,Christophe Del'Homme,Perrine Marquet,Jennifer C. Martin,Gisèle Pickering,Denis Ardid,Alain Eschalier,Claude Dubray,Harry J. Flint,Annick Bernalier-Donadille +12 more
TL;DR: The role of the gut microbiota in patho‐physiology of irritable bowel syndrome (IBS) is suggested by several studies but standard cultural and molecular methods used to date have not revealed specific and consistent IBS‐related groups of microbes.
Journal ArticleDOI
Immunopathogenesis of inflammatory bowel disease
TL;DR: Current knowledge on intestinal epithelial barrier alterations and on dysfunction of mucosal innate and acquired immune responses in IBD are presented to support the etiological hypothesis which argues that pathogenic intestinal bacteria and/or infectious agents initiate and perpetuate the inflammation of the gut through disruption of tolerance towards the commensal microbiota in an individual with genetic vulnerability.