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Caroline E. Childs
Researcher at University of Southampton
Publications - 48
Citations - 1872
Caroline E. Childs is an academic researcher from University of Southampton. The author has contributed to research in topics: Polyunsaturated fatty acid & Eicosapentaenoic acid. The author has an hindex of 21, co-authored 44 publications receiving 1309 citations. Previous affiliations of Caroline E. Childs include University of Reading & Southampton General Hospital.
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Journal ArticleDOI
Diet and Immune Function
TL;DR: The key functions of the immune system, and how it interacts with nutrients across the life course are outlined, including the role of macronutrients, micronutrient, and the gut microbiome in mediating immunological effects.
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Gender differences in the n-3 fatty acid content of tissues.
TL;DR: It is suggested that sex hormones act to modify plasma and tissue n-3 PUFA content, possibly by altering the expression of desaturase and elongase enzymes in the liver, which is currently under investigation.
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Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study
Caroline E. Childs,Henna Röytiö,Esa Alhoniemi,Agnes Fekete,Sofia D. Forssten,Natasa Hudjec,Ying Ni Lim,Cara J. Steger,Parveen Yaqoob,Kieran Tuohy,Robert A. Rastall,Arthur C. Ouwehand,Glenn R. Gibson +12 more
TL;DR: XOS induce bifidogenesis, improve aspects of the plasma lipid profile and modulate the markers of immune function in healthy adults, and the provision of XOS+Bi-07 as a synbiotic may confer further benefits due to the discrete effects of Bi-07 on the gut microbiota and markers ofimmune function.
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No Effect of Omega-3 Fatty Acid Supplementation on Cognition and Mood in Individuals with Cognitive Impairment and Probable Alzheimer's Disease: A Randomised Controlled Trial.
TL;DR: Elevating depleted levels of EPA and DHA through supplementation in individuals with CIND or AD was found to have negligible beneficial effect on their cognition or mood, confirming an overall negligible benefit of omega-3 PUFA supplementation for those with cognitive impairment and dementia.
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Synbiotics Alter Fecal Microbiomes, But Not Liver Fat or Fibrosis, in a Randomized Trial of Patients With Nonalcoholic Fatty Liver Disease
Eleonora Scorletti,Eleonora Scorletti,Eleonora Scorletti,Paul R. Afolabi,Paul R. Afolabi,Elizabeth A. Miles,Debbie E. Smith,Debbie E. Smith,Amal Almehmadi,Albandri Alshathry,Caroline E. Childs,Stefania Del Fabbro,Josh Bilson,Josh Bilson,Helen Moyses,Geraldine F. Clough,Jaswinder K. Sethi,Jaswinder K. Sethi,Janisha Patel,Mark Wright,David J. Breen,Charles Peebles,Angela Darekar,Richard Aspinall,Andrew Fowell,Joanna Dowman,Valerio Nobili,Valerio Nobili,Giovanni Targher,Nathalie M. Delzenne,Laure B. Bindels,Philip C. Calder,Philip C. Calder,Christopher D. Byrne,Christopher D. Byrne +34 more
TL;DR: In a randomized trial of patients with NAFLD, 1 y administration of a synbiotic combination (probiotic and prebiotic) altered fecal microbiomes but did not reduce liver fat content or markers of liver fibrosis.