C
Caroline Kühne
Researcher at Humboldt University of Berlin
Publications - 8
Citations - 348
Caroline Kühne is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Flagellum & Rotor (electric). The author has an hindex of 5, co-authored 8 publications receiving 177 citations.
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Journal ArticleDOI
Structure and Function of Stator Units of the Bacterial Flagellar Motor
Mònica Santiveri,Aritz Roa-Eguiara,Caroline Kühne,Navish Wadhwa,Haidai Hu,Howard C. Berg,Marc Erhardt,Nicholas M.I. Taylor +7 more
TL;DR: This work identifies key residues involved in torque generation and presents a detailed mechanistic model for motor function and switching of rotational direction in the stator unit.
Journal ArticleDOI
The Salmonella Spi1 virulence regulatory protein HilD directly activates transcription of the flagellar master operon flhDC
TL;DR: A novel transcriptional cross talk between the Spi1 and flagellar regulons where HilD transcriptionally activates flhDC gene expression by binding to nucleotides -68 to -24 upstream from the P5 transcriptional start site is reported.
Journal ArticleDOI
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
Julia A. Horstmann,Michele Lunelli,Hélène Cazzola,Johannes Heidemann,Caroline Kühne,Pascal Steffen,Sandra Szefs,Claire Rossi,Ravi K. Lokareddy,Chu Wang,Laurine Lemaire,Kelly T. Hughes,Charlotte Uetrecht,Charlotte Uetrecht,Hartmut Schlüter,Guntram A. Grassl,Theresia E. B. Stradal,Yannick Rossez,Michael Kolbe,Marc Erhardt +19 more
TL;DR: It is shown that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.
Posted ContentDOI
Structure and function of stator units of the bacterial flagellar motor
Mònica Santiveri,Aritz Roa-Eguiara,Caroline Kühne,Navish Wadhwa,Howard C. Berg,Marc Erhardt,Nicholas M.I. Taylor +6 more
TL;DR: This work identifies key residues involved in torque generation and presents a mechanistic model for motor function and switching of rotational direction in the bidirectional bacterial flagellar motor.
Journal ArticleDOI
Characterization of Novel Factors Involved in Swimming and Swarming Motility in Salmonella enterica Serovar Typhimurium.
Julia Andrea Deditius,Sebastian Felgner,Imke Spöring,Caroline Kühne,Michael Frahm,Manfred Rohde,Siegfried Weiß,Marc Erhardt +7 more
TL;DR: This work investigated the motility phenotype of 24 selected single gene deletions that were previously described to display swimming and swarming motility effects of Salmonella enterica.