Caroline T. Phan

TL;DR: Following toxic APAP exposure, distal lung CYP2E1 expression is associated with APAP metabolism, tissue injury, and oxidant, inflammatory, and endoplasmic reticulum signaling, and this previously unrecognized injury may help improve understanding of the relationship between APAP and pulmonary-related morbidity.

TL;DR: Observations suggest age-dependent differential airway responses to SARS-CoV-2 infection that could explain the distinction in pathogenesis between infants and adults.

TL;DR: The protective role of maternal antibodies against three categories of viruses: viruses that cause severe maternal disease outcomes with mainly indirect consequences to the fetus, those that are vertically transmitted from mother to their infants, and those that cause elevated disease severity among neonates and infants postnatally are discussed.

TL;DR: The immune profiles of pediatric and adult HIV elite controllers are compared, the characteristics of cellular and anatomic HIV reservoirs in pediatric populations are discussed, and the potential values of current cure strategies using immune-based therapies for long-term viral remission in the absence of ART are highlighted.

TL;DR: In this paper , two rhesus macaque monkey dam-infant pairs were inoculated with SARS-CoV-2 and conducted virological and transcriptomic analyses of the respiratory tract and evaluated systemic cytokine and Ab responses.