C
Carolyn E. King
Researcher at University of Tasmania
Publications - 38
Citations - 1423
Carolyn E. King is an academic researcher from University of Tasmania. The author has contributed to research in topics: Retina & Optic nerve. The author has an hindex of 19, co-authored 38 publications receiving 1328 citations. Previous affiliations of Carolyn E. King include University of Western Australia.
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Journal ArticleDOI
The cause of neuronal degeneration in Alzheimer's disease.
James C. Vickers,Tracey C. Dickson,Paul A. Adlard,Helen L. Saunders,Carolyn E. King,Graeme H. McCormack +5 more
TL;DR: Therapeutically, inhibition of the neuronal reaction to physical trauma may be a useful neuroprotective strategy in the earliest stages of Alzheimer's disease.
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Redefining the Role of Metallothionein within the Injured Brain: EXTRACELLULAR METALLOTHIONEINS PLAY AN IMPORTANT ROLE IN THE ASTROCYTE-NEURON RESPONSE TO INJURY*
Roger S. Chung,Milena Penkowa,Justin Dittmann,Carolyn E. King,Carole A. Bartlett,Johanne W. Asmussen,Juan Hidalgo,Javier Carrasco,Yee Kee J. Leung,Adam K. Walker,SJ Fung,Sarah A. Dunlop,Melinda Fitzgerald,Lyn Beazley,Meng Inn Chuah,James C. Vickers,Adrian K. West +16 more
TL;DR: Evidence is provided for a fundamentally different mode of action relying upon intercellular transfer from astrocytes to neurons, which in turn leads to uptake-dependent axonal regeneration and suggests that the protective functions of MT in the central nervous system should be widened to include extracellular and intra-neuronal roles.
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Neurochemical diversity of dystrophic neurites in the early and late stages of Alzheimer's disease.
TL;DR: Data indicate that dystrophic neurites may "mature" through neurofilament-abundant forms to the neurites containing the profoundly altered filaments labeled for tau, and suggest that beta-amyloid plaques are causing physical damage to surrounding axons.
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Erythropoietin is both neuroprotective and neuroregenerative following optic nerve transection
Carolyn E. King,Jennifer Rodger,Carole A. Bartlett,Tammy Esmaili,Sarah A. Dunlop,Lyn Beazley +5 more
TL;DR: In vivo evidence of both neuroregeneration and neuroprotection, taken together with the natural occurrence of EPO within the body and its ability to cross the blood-brain barrier, suggests that it offers promise as a therapeutic agent for central nerve repair.
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Relationship between participants' level of education and engagement in their completion of the Understanding Dementia Massive Open Online Course.
Lynette R. Goldberg,Erica Bell,Carolyn E. King,Ciaran O’Mara,Fran McInerney,Andrew Robinson,James C. Vickers +6 more
TL;DR: The high completion rate and level of engagement of participants across a broad spectrum of levels of education suggest that MOOCs can be successfully developed and delivered to students from diverse educational backgrounds.