C
Casper Larsen
Researcher at Aarhus University
Publications - 19
Citations - 304
Casper Larsen is an academic researcher from Aarhus University. The author has contributed to research in topics: Internal medicine & Primary aldosteronism. The author has an hindex of 9, co-authored 14 publications receiving 184 citations.
Papers
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Journal ArticleDOI
Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb
Pauline I.A. de Bruijn,Casper Larsen,Sebastian Frische,Nina Himmerkus,Helle A. Praetorius,Markus Bleich,Jens Leipziger +6 more
TL;DR: Furosemide-induced H+ secretion is a consequence of a drop in intracellular Na+ concentration, increasing the driving force for NHE3, and the role of the TAL in renal acid/base handling is emphasized.
Journal ArticleDOI
Structural and functional characterization of human and murine C5a anaphylatoxins
Janus Asbjørn Schatz-Jakobsen,Laure Yatime,Casper Larsen,Steen V. Petersen,Andreas Klos,Gregers R. Andersen +5 more
TL;DR: In this paper, the crystal structures of an antagonist version of human C5a, A8Δ71-73, and of murine C3a and C5aa-desArg are reported.
Journal ArticleDOI
Impaired Renal HCO3- Excretion in Cystic Fibrosis.
Peder Berg,Samuel L Svendsen,Mads V. Sorensen,Casper Larsen,Jesper Frank Andersen,Søren Jensen-Fangel,Majbritt Jeppesen,Rainer Schreiber,Inês Cabrita,Karl Kunzelmann,Jens Leipziger +10 more
TL;DR: The mechanism of secretin-induced urinary HCO3 - excretion is defined, metabolic alkalosis in patients with CF is explained, and feasibility of an in vivo human CF urine test to validate drug efficacy is suggested.
Journal ArticleDOI
Structural assembly of the megadalton-sized receptor for intestinal vitamin B 12 uptake and kidney protein reabsorption
Casper Larsen,Anders Etzerodt,Mette Madsen,Karsten Skjødt,Søren K. Moestrup,Christian Brix Folsted Andersen +5 more
TL;DR: The 2.3 Å crystal structure of AMN in complex with the amino-terminal region of cubilin is presented and effects of known human mutations causing IGS are explained by the structural information.
Journal ArticleDOI
Change of cardiac function, but not form, in postprandial pythons.
TL;DR: It is suggested that postprandial cardiac growth should be regarded as a facultative rather than obligatory component of the renowned postpr andial response of pythons.