C
Catherine Monnot
Researcher at PSL Research University
Publications - 49
Citations - 2672
Catherine Monnot is an academic researcher from PSL Research University. The author has contributed to research in topics: Angiotensin II & Angiogenesis. The author has an hindex of 24, co-authored 47 publications receiving 2386 citations. Previous affiliations of Catherine Monnot include Centre national de la recherche scientifique & Collège de France.
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Journal ArticleDOI
Angiopoietin-Like 4 Is a Proangiogenic Factor Produced during Ischemia and in Conventional Renal Cell Carcinoma
Sébastien Le Jan,Céline Amy,Aurélie Cazes,Catherine Monnot,Noël Lamandé,Judith Favier,Josette Philippe,Mathilde Sibony,Jean-Marie Gasc,Pierre Corvol,Stéphane Germain +10 more
TL;DR: ANGPTL4, originally identified as a peroxisome proliferator-activated receptor alpha and gamma target gene, has potential for use as a new diagnostic tool and a potential therapeutic target, modulating angiogenesis both in tumors and in ischemic tissues.
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Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness
Ariane Galaup,Aurélie Cazes,Sébastien Le Jan,Josette Philippe,Elisabeth Connault,Emmanuelle Le Coz,H. Mekid,Lluis M. Mir,Paule Opolon,Pierre Corvol,Catherine Monnot,Stéphane Germain +11 more
TL;DR: Results show that ANGPTL4, through its action on both vascular and tumor compartments, prevents the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness.
Journal ArticleDOI
Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.
Catherine Monnot,Claire Bihoreau,Sophie Conchon,Kathleen M. Curnow,Pierre Corvol,Eric Clauser +5 more
TL;DR: In this paper, the roles of 7 amino acids of the rat AT1A receptor in ligand binding and signaling were investigated by performing functional assays of individual receptor mutants expressed in COS and Chinese hamster ovary cells.
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Extracellular Matrix–Bound Angiopoietin-Like 4 Inhibits Endothelial Cell Adhesion, Migration, and Sprouting and Alters Actin Cytoskeleton
Aurélie Cazes,Ariane Galaup,Clémence Chomel,Marine Bignon,Nicolas Bréchot,Sébastien Le Jan,Holger Weber,Pierre Corvol,Laurent Muller,Stéphane Germain,Catherine Monnot +10 more
TL;DR: It is observed in a mouse model of hindlimb ischemia that the mRNA upregulation in the vessels correlates with the accumulation of the full-length protein in ischemic tissues, which negatively regulates their angiogenic capacities through an autocrine pathway.
Journal ArticleDOI
Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane
Marine Bignon,Marine Bignon,Marine Bignon,Cathy Pichol-Thievend,Cathy Pichol-Thievend,Cathy Pichol-Thievend,Julie Hardouin,Marilyne Malbouyres,Nicholas Brechot,Nicholas Brechot,Nicholas Brechot,Luiz Nasciutti,Luiz Nasciutti,Luiz Nasciutti,A. Barret,A. Barret,A. Barret,Jérémie Teillon,Jérémie Teillon,Jérémie Teillon,Emilie Guillon,Eric Etienne,Eric Etienne,Eric Etienne,Michel Caron,Raymonde Joubert-Caron,Catherine Monnot,Catherine Monnot,Catherine Monnot,Florence Ruggiero,Laurent Muller,Laurent Muller,Laurent Muller,Stéphane Germain,Stéphane Germain,Stéphane Germain +35 more
TL;DR: This study provides the first evidence for the role of LOXL2 in regulating angiogenesis through collagen IV scaffolding and suggests a major role for this enzyme in the organization of endothelial basal lamina and in the downstream mechanotransductive signaling.