Showing papers by "Cécile M. Ronckers published in 2007"
Journal Article•
TL;DR: Pediatric CT scans in Israel may result in a small but not negligible increased lifetime risk for cancer mortality, and because of the uncertainty regarding radiation effects at low doses, estimates of CT-related cancer mortality should be considered with caution.
Abstract: Background: The use of computed tomography in Israel has been growing rapidly during recent decades. The major drawback of this important technology is the exposure to ionizing radiation, especially among children who have increased organ radiosensitivity and a long lifetime to potentially develop radiation-related cancer. Objective: To estimate the number of excess lifetime cancer deaths related to annual CT scans performed in children in Israel. Methods: We used CT scan utilization data from 1999 to 2003 obtained from the second largest health management organization in the country to project age and gender-specific CT scan use nationwide. Based on published organ doses for common CT examinations and radiation-related cancer mortality risk estimates from studies in survivors of the atomic bomb, we estimated the excess lifetime risks for cancer mortality attributed to use of CT in children and adolescents (up to 18 years old) in Israel. Results: We estimated that 17,686 pediatric scans were conducted annually in Israel during 1999–2003. We project that 9.5 lifetime deaths would be associated with 1 year of pediatric CT scanning. This number represents an excess of 0.29% over the total number of patients who are eventually estimated to die from cancer in their lifetime. Conclusions: Pediatric CT scans in Israel may result in a small but not negligible increased lifetime risk for cancer mortality. Because of the uncertainty regarding radiation effects at low doses, our estimates of CT-related cancer mortality should be considered with caution. Nevertheless, physicians, CT technologists, and health authorities should work together to minimize the radiation dose for children to as low as reasonably achievable and encourage responsible use of this essential diagnostic tool.
146 citations
National Institutes of Health1, Boston Children's Hospital2, Washington University in St. Louis3, University of Minnesota4, Emory University5, University of Texas MD Anderson Cancer Center6, University of Pennsylvania7, Fred Hutchinson Cancer Research Center8, Ohio State University9, Silver Spring Networks10, Stanford University11, St. Jude Children's Research Hospital12
TL;DR: Survivors of childhood NHL, particularly those treated with chest RT, are at continued increased risk of early mortality and solid tumor SMNs.
71 citations
Lawrence Berkeley National Laboratory1, National Institute for Occupational Safety and Health2, University of Texas Medical Branch3, University of Oxford4, National Institutes of Health5, Columbia University6, Lawrence Livermore National Laboratory7, Arizona State University8, University of Amsterdam9, Centers for Disease Control and Prevention10, University of Southern California11, Colorado State University12
TL;DR: This research presents a state-of-the-art virtual reality system that automates the very labor-intensive and therefore time-consuming and expensive and therefore expensive and time-heavy and expensive process of designing and implementing virtual reality systems.
Abstract: Amy Kronenberg, Sc.D., Co-Chair, Lawrence Berkeley National Laboratory Mary Schubauer-Berigan, Ph.D., Co-Chair, National Institute for Occupational Safety and Health Martin Colman, M.D., The University of Texas Medical Branch Sarah Darby, Ph.D., University of Oxford Ethel Gilbert, Ph.D., National Cancer Institute Geoffrey Howe, Ph.D., Columbia University Irene Jones, Ph.D., Lawrence Livermore National Laboratory Kenneth Mossman, Ph.D., Arizona State University Cécile Ronckers, Ph.D., Academic Medical Center/Emma Children’s Hospital, The Netherlands James Smith, Ph.D., Centers for Disease Control and Prevention Dan Stram, Ph.D., University of Southern California Robert Ullrich, Ph.D., Colorado State University John Zimbrick, Ph.D., Colorado State University