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Cecilia Isabel Muglia
Researcher at National University of La Plata
Publications - 24
Citations - 638
Cecilia Isabel Muglia is an academic researcher from National University of La Plata. The author has contributed to research in topics: Mutant & Galectin. The author has an hindex of 11, co-authored 23 publications receiving 558 citations. Previous affiliations of Cecilia Isabel Muglia include National Scientific and Technical Research Council.
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Journal ArticleDOI
Glutathione is involved in environmental stress responses in Rhizobium tropici, including acid tolerance.
Pablo M. Riccillo,Cecilia Isabel Muglia,F. J. de Bruijn,Andrew J. Roe,Ian R. Booth,Orlando Mario Aguilar +5 more
TL;DR: The data show that in R. tropici the production of glutathione is essential for growth in extreme environmental conditions, and the mutant strain CIAT899-13T2 induced effective nodules; however, it was found to be outcompeted by the wild-type strain in coinoculation experiments.
Journal ArticleDOI
Glutathione plays a fundamental role in growth and symbiotic capacity of Sinorhizobium meliloti
Judith Harrison,Alexandre Jamet,Cecilia Isabel Muglia,Ghislaine Van de Sype,O. Mario Aguilar,Alain Puppo,Pierre Frendo +6 more
TL;DR: Results show that GSH plays a critical role in the growth of S. meliloti and during its interaction with the plant partner, suggesting that both mutant strains are under oxidative stress.
Journal ArticleDOI
Vanadium and cancer treatment: antitumoral mechanisms of three oxidovanadium(IV) complexes on a human osteosarcoma cell line.
Ignacio E. León,Nataliya Butenko,A.L. Di Virgilio,Cecilia Isabel Muglia,Enrique J. Baran,Isabel Cavaco,Susana B. Etcheverry +6 more
TL;DR: Results showed a good relationship between the bioactivity of the complexes and their structures since VO(oda)phen presented the most potent antitumor action in human osteosarcoma cells followed by VO (oda)bipy and then by VO(ODA) according to the number of intercalating heterocyclic moieties.
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Antitumor properties of a vanadyl(IV) complex with the flavonoid chrysin [VO(chrysin)2EtOH]2 in a human osteosarcoma model: the role of oxidative stress and apoptosis
Ignacio E. León,A.L. Di Virgilio,V. Porro,Cecilia Isabel Muglia,Luciana G. Naso,Patricia A.M. Williams,Mariela Bollati-Fogolín,Susana B. Etcheverry +7 more
TL;DR: Reactive oxygen species (ROS) and the alterations in the GSH/GSSG ratio underlie the main mechanisms of action of VOchrys, which is a cell death modulator and a promissory complex to be used in cancer treatments.
Journal ArticleDOI
Glutathione produced by Rhizobium tropici is important to prevent early senescence in common bean nodules
Cecilia Isabel Muglia,Glenda Comai,Etile Dolores Spegazzini,Pablo M. Riccillo,O. Mario Aguilar +4 more
TL;DR: Results provide a direct evidence of the role of bacterial glutathione in protecting nodules from reactive oxygen species, which may determine nodule senescence.