C
Cees J. H. M. van Laarhoven
Researcher at Radboud University Nijmegen Medical Centre
Publications - 12
Citations - 1913
Cees J. H. M. van Laarhoven is an academic researcher from Radboud University Nijmegen Medical Centre. The author has contributed to research in topics: Randomized controlled trial & Pancreatitis. The author has an hindex of 8, co-authored 12 publications receiving 1759 citations.
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Journal ArticleDOI
Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial
Marc G. Besselink,Hjalmar C. van Santvoort,Erik Buskens,Erik Buskens,Marja A. Boermeester,Harry van Goor,Harro M. Timmerman,Vincent B. Nieuwenhuijs,Thomas L. Bollen,Bert van Ramshorst,Ben J.M. Witteman,Camiel Rosman,Rutger J. Ploeg,Menno A. Brink,Alexander F. Schaapherder,Cornelis H. C. Dejong,Peter J. Wahab,Cees J. H. M. van Laarhoven,Erwin van der Harst,Casper H.J. van Eijck,Miguel A. Cuesta,Louis M. A. Akkermans,Hein G. Gooszen +22 more
TL;DR: In patients with predicted severe acute pancreatitis, probiotic prophylaxis with this combination of probiotic strains did not reduce the risk of infectious complications and was associated with an increased risk of mortality.
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Results and Complications after Ileal Pouch Anal Anastomosis: A Meta-Analysis of 43 Observational Studies Comprising 9,317 Patients
Willem E. Hueting,Erik Buskens,Ingeborg van der Tweel,Hein G. Gooszen,Cees J. H. M. van Laarhoven +4 more
TL;DR: Current techniques for restorative surgery after proctocolectomy are associated with non-negligible complication rates and leave room for improvement and continuation of development of alternative procedures.
Journal ArticleDOI
Open versus laparoscopic (assisted) ileo pouch anal anastomosis for ulcerative colitis and familial adenomatous polyposis
Usama Ahmed Ali,Frederik Keus,J.T. Heikens,Willem A. Bemelman,Stephane V. Berdah,H. G. Gooszen,Cees J. H. M. van Laarhoven +6 more
TL;DR: Short-term advantages of the laparoscopic IPAA seem to be limited and their clinical significance is arguable, so large high-quality trials focusing on differences regarding specific postoperative complications, cosmesis, quality of life and costs are needed.
Journal ArticleDOI
Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN13975868]
Marc G. Besselink,Hjalmar C. van Santvoort,Vincent B. Nieuwenhuijs,Marja A. Boermeester,Thomas L. Bollen,Erik Buskens,Cornelis H. C. Dejong,Casper H.J. van Eijck,Harry van Goor,Sijbrand S. Hofker,Johan S. Laméris,Maarten S. van Leeuwen,Rutger J. Ploeg,Bert van Ramshorst,Alexander F. Schaapherder,Miguel A. Cuesta,Esther C. J. Consten,Dirk J. Gouma,Erwin van der Harst,Eric J. Hesselink,Lex P. J. Houdijk,Tom M. Karsten,Cees J. H. M. van Laarhoven,Jean-Pierre E. N. Pierie,Camiel Rosman,Ernst Jan Spillenaar Bilgen,Robin Timmer,Ingeborg van der Tweel,Ralph J. de Wit,Ben J.M. Witteman,Hein G. Gooszen +30 more
TL;DR: To demonstrate that the 'step-up approach' can reduce the major morbidity and mortality rate from 45 to 16%, with 80% power at 5% alpha, a total sample size of 88 patients was calculated.
Journal ArticleDOI
Update of complications and functional outcome of the ileo-pouch anal anastomosis: overview of evidence and meta-analysis of 96 observational studies.
Sharonne de Zeeuw,Usama Ahmed Ali,Rogier Donders,Willem E. Hueting,Frederik Keus,Cees J. H. M. van Laarhoven +5 more
TL;DR: This review provides up to date outcome estimates of the IPAA procedure that can be useful as reference values for practice and research and shows a reduction in pouch failure over time.