C
Céline Beauvillain
Researcher at University of Angers
Publications - 50
Citations - 1064
Céline Beauvillain is an academic researcher from University of Angers. The author has contributed to research in topics: Medicine & Innate immune system. The author has an hindex of 12, co-authored 40 publications receiving 916 citations. Previous affiliations of Céline Beauvillain include French Institute of Health and Medical Research.
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Journal ArticleDOI
Neutrophils efficiently cross-prime naive T cells in vivo
Céline Beauvillain,Yves Delneste,Mari Scotet,Audrey Peres,Hugues Gascan,Pierre Guermonprez,Vincenzo Barnaba,Pascale Jeannin +7 more
TL;DR: These data are the first demonstration that neutrophils cross-prime CD8+ T cells in vivo and suggest that they may constitute, together with professional antigen-presenting cells, an attractive target to induce cytotoxic T Cells in vaccines.
Journal ArticleDOI
CCR7 is involved in the migration of neutrophils to lymph nodes
Céline Beauvillain,Céline Beauvillain,Pierre Cunin,Pierre Cunin,Andrea Doni,Mari Scotet,Mari Scotet,Sébastien Jaillon,Sébastien Jaillon,Sébastien Jaillon,Marie Line Loiry,Giovanni Magistrelli,Krzysztof Masternak,Alain Chevailler,Alain Chevailler,Yves Delneste,Yves Delneste,Pascale Jeannin,Pascale Jeannin +18 more
TL;DR: CCR7 is identified as a chemokine receptor involved in the migration of neutrophils to the lymph nodes and intradermally injected interleukin-17-and granulocyte-macrophage colony-stimulating factor-stimulated neutrophil migrate to the draining lymph nodes.
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[Innate immunity: structure and function of TLRs].
TL;DR: The role of TLRs as molecular interfaces between innate and adaptive immunity is highlighted, highlighting the nature of the immune response generated against the microbial molecules.
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Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses.
Pierre Cunin,Céline Beauvillain,Charline Miot,Jean-François Augusto,Laurence Preisser,Simon Blanchard,Pascale Pignon,Mari Scotet,Erwan Garo,Isabelle Frémaux,Alain Chevailler,Jean-François Subra,Patrick Blanco,Mark R. Wilson,Pascale Jeannin,Yves Delneste +15 more
TL;DR: Clusterin (Clu), an extracellular chaperone, exhibits characteristics of soluble innate immunity receptors, as assessed by its ability to bind some bacteria strains, and is identified as a new molecule partner involved in apoptotic cell efferocytosis.
Journal ArticleDOI
Neonatal and adult microglia cross‐present exogenous antigens
Céline Beauvillain,Sabrina Donnou,Ulrich Jarry,Mari Scotet,Hugues Gascan,Yves Delneste,Pierre Guermonprez,Pascale Jeannin,Dominique Couez +8 more
TL;DR: This first demonstration of the cross‐presentation property of microglia offers novel therapeutic approaches to modulate CD8 T‐cell responses in the brain.