C
Celine Gomez
Researcher at Wellcome Trust Sanger Institute
Publications - 11
Citations - 1173
Celine Gomez is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome-wide association study & DNA damage. The author has an hindex of 8, co-authored 9 publications receiving 866 citations. Previous affiliations of Celine Gomez include Stowers Institute for Medical Research & King's College London.
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Journal ArticleDOI
Control of segment number in vertebrate embryos
Celine Gomez,Ertuğrul M. Özbudak,Joshua P. Wunderlich,Diana P. Baumann,Julian Lewis,Olivier Pourquié,Olivier Pourquié +6 more
TL;DR: Evidence is presented that in all of these species a similar ‘clock-and-wavefront’ mechanism operates to control somitogenesis; in snake embryos, however, the segmentation clock rate is much faster relative to developmental rate than in other amniotes, leading to a greatly increased number of smaller-sized somites.
Journal ArticleDOI
A Compendium of Mutational Signatures of Environmental Agents
Jill E. Kucab,Xueqing Zou,Xueqing Zou,Sandro Morganella,Madeleine Joel,A. Scott Nanda,Eszter Nagy,Celine Gomez,Andrea Degasperi,Andrea Degasperi,Rebecca Harris,Rebecca Harris,Stephen P. Jackson,Volker M. Arlt,David H. Phillips,Serena Nik-Zainal,Serena Nik-Zainal +16 more
TL;DR: This compendium of experimentally induced mutational signatures permits further exploration of roles of environmental agents in cancer etiology and underscores how human stem cell DNA is directly vulnerable to environmental agents.
Journal ArticleDOI
Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.
Emanuel Rognoni,Celine Gomez,Angela Oliveira Pisco,Emma L. Rawlins,Benjamin D. Simons,Fiona M. Watt,Ryan R. Driskell +6 more
TL;DR: The data support a model whereby postnatal loss of hair forming ability in wounds reflects elevated dermal Wnt/β-catenin activation in the wound bed, increasing the abundance of fibroblasts that are unable to induce HF formation.
Journal ArticleDOI
Developmental control of segment numbers in vertebrates
Celine Gomez,Olivier Pourquié +1 more
TL;DR: It is proposed that during development, dissociation of the Hox- and segmentation-clock-dependent vertebral patterning systems explains the enormous diversity of vertebral formulae observed in vertebrates.
Journal ArticleDOI
The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages that Are Differentially Regulated by Wnt, Edaradd, and Lrig1
TL;DR: It is concluded that the different IFE differentiation compartments are maintained by distinct stem cell populations and are regulated by epidermal and dermal signals.