C
Céline Verstuyft
Researcher at University of Paris-Sud
Publications - 140
Citations - 5779
Céline Verstuyft is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 35, co-authored 122 publications receiving 5337 citations. Previous affiliations of Céline Verstuyft include Pierre-and-Marie-Curie University & Université Paris-Saclay.
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Journal ArticleDOI
Genetic Determinants of Response to Clopidogrel and Cardiovascular Events
Tabassome Simon,Céline Verstuyft,Murielle Mary-Krause,Lina Quteineh,Elodie Drouet,Nicolas Meneveau,P. Gabriel Steg,Jean Ferrières,Nicolas Danchin,Laurent Becquemont,Abstr Act +10 more
TL;DR: Among patients with an acute myocardial infarction who were receiving clopidogrel, those carrying CYP2C19 loss-of-function alleles had a higher rate of subsequent cardiovascular events than those who were not, particularly marked among the patients undergoing percutaneous coronary intervention.
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Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity
Laurent Bodin,Céline Verstuyft,David-Alexandre Trégouët,Annie Robert,Liliane Dubert,Christian Funck-Brentano,Patrice Jaillon,Philippe Beaune,Pierre Laurent-Puig,Laurent Becquemont,Marie-Anne Loriot +10 more
TL;DR: The simple genotyping of 2 single-nucleotide polymorphisms (SNPs), VKORC1 -1639G>A or 1173C>T and the CYP2C9*3 polymorphisms, could predict a high risk of overdose before initiation of anticoagulation with acenocoumarol, and provide a safer and more individualized antICOagulant therapy.
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Association of the Multidrug Resistance-1 Gene Single-Nucleotide Polymorphisms with the Tacrolimus Dose Requirements in Renal Transplant Recipients
Dany Anglicheau,Céline Verstuyft,Pierre Laurent-Puig,Laurent Becquemont,Marie-Hélène Schlageter,Bruno Cassinat,Philippe Beaune,Christophe Legendre,Eric Thervet +8 more
TL;DR: Genotype monitoring of the MDR1 gene reliably predicts the optimal dose of tacrolimus in renal transplant recipients and may predict the initial daily dose needed by individual patients to obtain adequate immunosuppression.
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Effect of grapefruit juice on digoxin pharmacokinetics in humans
Laurent Becquemont,Céline Verstuyft,Reinhold Kerb,Ulrich Brinkmann,Martine Lebot,Patrice Jaillon,Christian Funck-Brentano +6 more
TL;DR: Whether grapefruit juice alters the bioavailability of digoxin, a P‐glycoprotein substrate, is investigated to determine whether the magnitude of the pharmacokinetic interaction was influenced by P‐ Glycoprotein genetic polymorphism.
Journal ArticleDOI
Environmental and genetic factors associated with morphine response in the postoperative period.
Laurent Coulbault,Marc Beaussier,Céline Verstuyft,Henri Weickmans,Liliane Dubert,David-Alexandre Trégouët,Christelle Descot,Yann Parc,André Lienhart,Patrice Jaillon,Laurent Becquemont +10 more
TL;DR: The aim of this study was to investigate the respective influence of genetic and nongenetic factors on morphine dose requirements and adverse effects after colorectal surgery.