C
Celso T. Mendes-Junior
Researcher at Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto
Publications - 124
Citations - 2815
Celso T. Mendes-Junior is an academic researcher from Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto. The author has contributed to research in topics: Haplotype & Human leukocyte antigen. The author has an hindex of 26, co-authored 115 publications receiving 2345 citations. Previous affiliations of Celso T. Mendes-Junior include University of São Paulo.
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Journal ArticleDOI
The genetic structure of 3′untranslated region of the HLA-G gene: polymorphisms and haplotypes
Erick C. Castelli,Celso T. Mendes-Junior,N. H. S. Deghaide,R. S. de Albuquerque,Yara Costa Netto Muniz,Renata Simões,Edgardo D. Carosella,Philippe Moreau,Eduardo Antônio Donadi +8 more
TL;DR: A high linkage disequilibrium among the variation sites was detected, especially among the 14-bp insertion and the alleles +3142G and +3187A, all previously associated with low mRNA availability, demonstrating that their effects are not independent.
Journal ArticleDOI
Polymorphic Sites at the 3’ Untranslated Region of the HLA-G Gene Are Associated with Differential hla-g Soluble Levels in the Brazilian and French Population
Gustavo Martelli-Palomino,Gustavo Martelli-Palomino,Gustavo Martelli-Palomino,João Alexandre Trés Pancotto,João Alexandre Trés Pancotto,João Alexandre Trés Pancotto,Yara Costa Netto Muniz,Yara Costa Netto Muniz,Celso T. Mendes-Junior,Erick C. Castelli,Juliana Doblas Massaro,Irene Krawice-Radanne,Irene Krawice-Radanne,Isabelle Poras,Isabelle Poras,Vera Rebmann,Edgardo D. Carosella,Edgardo D. Carosella,Nathalie Rouas-Freiss,Nathalie Rouas-Freiss,Philippe Moreau,Philippe Moreau,Eduardo Antônio Donadi +22 more
TL;DR: The analyses of 3’UTR haplotypes showed that UTR-1 (DelTGCCCGC) was associated with higher expression of sHLA-G, whereas U TRs (UTR-2/3/4/6) exhibited intermediate levels, and the identification of individuals genetically programmed to differentially express HLA-G may help on defining novel strategies to control the immune response against the underlying disorder.
Journal ArticleDOI
In silico analysis of microRNAS targeting the HLA-G 3' untranslated region alleles and haplotypes.
Erick C. Castelli,Philippe Moreau,Alynne Oya e Chiromatzo,Celso T. Mendes-Junior,Luciana C. Veiga-Castelli,Layale Yaghi,Silvana Giuliatti,Edgardo D. Carosella,Eduardo Antônio Donadi +8 more
TL;DR: Results suggest that these miRNAs might play a relevant role on the HLA-G expression pattern, and the lowest free energies that could potentially lead to an mRNA degradation or translational repression are ranked.
Journal ArticleDOI
A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution
Erick C. Castelli,Celso T. Mendes-Junior,Luciana C. Veiga-Castelli,Michel Roger,Philippe Moreau,Eduardo Antônio Donadi +5 more
TL;DR: Several lines of evidence indicate that HLA-G polymorphisms at the 5'-upstream regulatory region (5' URR) and 3'-untranslated region (3' UTR) may influence the Hla-G expression levels, and several lines ofevidence for balancing selection acting on the regulatory regions are reported.
Journal ArticleDOI
HLA-DRB association in neuromyelitis optica is different from that observed in multiple sclerosis
Doralina Guimaraães Brum,Amilton Antunes Barreira,Antônio Carlos dos Santos,Damacio Ramón Kaimen-Maciel,Marcelo Matiello,Roberta Martins da Silva Costa,N. H. S. Deghaide,Laudo Silva Costa,Paulo Louzada-Junior,Paula Rejane Beserra Diniz,Elizabeth Regina Comini-Frota,Celso T. Mendes-Junior,Eduardo Antônio Donadi +12 more
TL;DR: The results indicate that the DRB profile of NMO patients is different from that observed for MS patients, further corroborating the distinction between NMO and MS.