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Changlian Zhu
Researcher at University of Gothenburg
Publications - 208
Citations - 16429
Changlian Zhu is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Neuroprotection & Apoptosis. The author has an hindex of 50, co-authored 183 publications receiving 13346 citations. Previous affiliations of Changlian Zhu include Boston Children's Hospital & Karolinska Institutet.
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Umbilical cord blood stem cell therapy in premature brain injury: Opportunities and challenges.
TL;DR: This review focuses on recent advances on the efficacy of UCB‐derived stem cell therapy in preterm infants with brain injury, and discusses the potential mechanisms behind their therapeutic effects as well as application strategies for future preclinical and clinical trials.
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Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma
TL;DR: In this paper, the expression of TPX2 and its significance in esophageal squamous cell carcinoma (ESCC) tissue and approach relationship between the TPX 2 and clinicopathological characteristic of esophagescell carcinoma was explored.
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Birth Asphyxia Is Associated With Increased Risk of Cerebral Palsy: A Meta-Analysis.
Shan Zhang,Bingbing Li,Xiaoli Zhang,Changlian Zhu,Changlian Zhu,Changlian Zhu,Xiaoyang Wang,Xiaoyang Wang +7 more
TL;DR: The findings suggest that the incidence of cerebral palsy in neonates (≥35 weeks' gestation) with perinatal asphyxia is significantly higher compared to that in the healthy neonate population.
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Grafting of neural stem and progenitor cells to the hippocampus of young, irradiated mice causes gliosis and disrupts the granule cell layer
Yoshiaki Sato,Yoshiaki Sato,Noriko Shinjyo,Machiko Sato,Kazuhiro Osato,Kazuhiro Osato,Changlian Zhu,Changlian Zhu,Marcela Pekna,Hans G. Kuhn,Klas Blomgren,Klas Blomgren +11 more
TL;DR: It is demonstrated that age and interval between IR and grafting can affect survival and differentiation of grafted NSPCs, and the observed long-term gliosis and degeneration warrant caution in the context of NSPC grafting for therapeutical purposes.
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Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia–ischemia
Juan Lantero Rodriguez,Yaodong Zhang,Yaodong Zhang,Tao Li,Tao Li,Tao Li,Cuicui Xie,Cuicui Xie,Yanyan Sun,Yanyan Sun,Yiran Xu,Yiran Xu,Kai Zhou,Kai Zhou,Kaiming Huo,Kaiming Huo,Kaiming Huo,Yafeng Wang,Yafeng Wang,Yafeng Wang,Xiaoyang Wang,Daniel Andersson,Anders Ståhlberg,Qinghe Xing,Carina Mallard,Henrik Hagberg,Nazanine Modjtahedi,Guido Kroemer,Klas Blomgren,Klas Blomgren,Changlian Zhu,Changlian Zhu +31 more
TL;DR: Results indicate that AIF2 deficiency exacerbates free radical production and HI-induced neonatal brain injury in mice and is linked to increased oxidative stress but not to caspase-dependent or -independent apoptosis pathways.