C
Changlian Zhu
Researcher at University of Gothenburg
Publications - 208
Citations - 16429
Changlian Zhu is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Neuroprotection & Apoptosis. The author has an hindex of 50, co-authored 183 publications receiving 13346 citations. Previous affiliations of Changlian Zhu include Boston Children's Hospital & Karolinska Institutet.
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Journal ArticleDOI
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia
Changlian Zhu,Changlian Zhu,Ulrika Hallin,Yasuhiko Ozaki,Rita Grandér,Kliment Gatzinsky,Ben A. Bahr,Jan-Olof Karlsson,Futoshi Shibasaki,Henrik Hagberg,Klas Blomgren,Klas Blomgren +11 more
TL;DR: It is found that the total level of Bcl-2 decreased after HI in vivo and after ionophore challenge in cultured human neuroblastoma (IMR-32) cells in vitro, suggesting cross-talk between excitotoxic and apoptotic mechanisms.
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Methylenetetrahydrofolate reductase gene polymorphisms and cerebral palsy in Chinese infants
Xiuyong Cheng,Xiuyong Cheng,Tongchuan Li,Honglian Wang,Dengna Zhu,Caiyun Ma,Bingxiang Ma,Yinghong Wang,Junyu Zhang,Luo Guo,Lei Wang,Liu Yun,Shiting Chen,Zedong Jiang,Zedong Jiang,Lin He,Lin He,Changlian Zhu,Qinghe Xing +18 more
TL;DR: This study provides the first evidence pointing to a MTHFR gene polymorphism as a potential risk factor for CP combined with MR.
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Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia
Yanyan Sun,Yu Zhang,Yu Zhang,Xiaoyang Wang,Xiaoyang Wang,Klas Blomgren,Klas Blomgren,Changlian Zhu,Changlian Zhu +8 more
TL;DR: These findings demonstrate that AIF downregulation provides not only long-term overall neuroprotection after HI, but also protects neural progenitor cells, thereby rescuing hippocampal neurogenesis.
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Association of Interleukin 6 gene polymorphisms with genetic susceptibilities to spastic tetraplegia in males: a case-control study.
Mingjie Chen,Tongchuan Li,Sheyu Lin,Sheyu Lin,Dan Bi,Dengna Zhu,Qing Shang,Caiyun Ma,Honglian Wang,Honglian Wang,Lei Wang,Lei Wang,Yiting Zhang,Yiting Zhang,Lin He,Lin He,Changlian Zhu,Changlian Zhu,Qinghe Xing,Qinghe Xing +19 more
TL;DR: Genetic variation of the IL6 gene may influence susceptibility to spastic tetraplegia in males and its role in cerebral palsy deserves further evaluation in a large-scale and well-designed study.
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The effect of vitamin D supplementation in treatment of children with autism spectrum disorder: a systematic review and meta-analysis of randomized controlled trials
Bingbing Li,Yiran Xu,Xiaoli Zhang,Lingling Zhang,Yanan Wu,Xiaoyang Wang,Xiaoyang Wang,Changlian Zhu,Changlian Zhu,Changlian Zhu +9 more
TL;DR: Vitamin D supplementation appears to be beneficial for hyperactivity but not for core symptoms or other co-existing behaviors and conditions of ASD among individuals with low serum vitamin D levels at baseline are needed.