Changlian Zhu

TL;DR: It is demonstrated that preterm pregnancy loss in response to intrauterine inflammation was enhanced by disruption of the IL-18 gene and/or IL- 18 neutralization, events that may relate to exaggerated Th1 responses because of an increased IL-12/IL-18 ratio.

TL;DR: The data imply that NMDA receptors are involved in the activation of apoptotic processes in the immature brain after HI, and reduce injury, cells positive for active caspase-3, and DNA fragmentation in the cerebral cortex.

TL;DR: The WINROP system had a sensitivity of 87.5% in a Chinese population for the early identification of infants that developed severe ROP and was identified in this alarm group.

TL;DR: Analysis of postmortem brains from human preterm infants with periventricular leukomalacia and two animal models of preterm brain injury highlighted unique features of injury in the developing brain, where γδT cells function as initiators of injury independently of common γ δT-cell–associated cytokines.

TL;DR: It is demonstrated that X’chromosome‐linked inhibitor of apoptosis protein (XIAP) counteracts oxidative stress in two essentially different disease‐related models of brain injury, hypoxia‐ischemia and irradiation, and may provide the basis for development of novel protective strategies for both acute and chronic neurodegenerative diseases.