The objective of this paper is to give a comprehensive introduction to applied cryptography with an engineer or computer scientist in mind. The emphasis is on the knowledge needed to create practical systems which supports integrity, confidentiality, or authenticity. Topics covered includes an introduction to the concepts in cryptography, attacks against cryptographic systems, key use and handling, random bit generation, encryption modes, and message authentication codes. Recommendations on algorithms and further reading is given in the end of the paper. This paper should make the reader able to build, understand and evaluate system descriptions and designs based on the cryptographic components described in the paper.

[서평]「Applied Cryptography」

Silver nanoparticles (AgNPs) can be synthesized from a variety of techniques including physical, chemical and biological routes. They have been widely used as nanomaterials for manufacturing cosmetic and healthcare products, antimicrobial textiles, wound dressings, antitumor drug carriers, etc. due to their excellent antimicrobial properties. Accordingly, AgNPs have gained access into our daily life, and the inevitable human exposure to these nanoparticles has raised concerns about their potential hazards to the environment, health, and safety in recent years. From in vitro cell cultivation tests, AgNPs have been reported to be toxic to several human cell lines including human bronchial epithelial cells, human umbilical vein endothelial cells, red blood cells, human peripheral blood mononuclear cells, immortal human keratinocytes, liver cells, etc. AgNPs induce a dose-, size- and time-dependent cytotoxicity, particularly for those with sizes ≤10 nm. Furthermore, AgNPs can cross the brain blood barrier of mice through the circulation system on the basis of in vivo animal tests. AgNPs tend to accumulate in mice organs such as liver, spleen, kidney and brain following intravenous, intraperitoneal, and intratracheal routes of administration. In this respect, AgNPs are considered a double-edged sword that can eliminate microorganisms but induce cytotoxicity in mammalian cells. This article provides a state-of-the-art review on the synthesis of AgNPs, and their applications in antimicrobial textile fabrics, food packaging films, and wound dressings. Particular attention is paid to the bactericidal activity and cytotoxic effect in mammalian cells.

Bactericidal and Cytotoxic Properties of Silver Nanoparticles.

Solid composite electrolytes (SCEs) that combine the advantages of solid polymer electrolytes (SPEs) and inorganic ceramic electrolytes (ICEs) present acceptable ionic conductivity, high mechanical strength, and favorable interfacial contact with electrodes, which greatly improve the electrochemical performance of all-solid-state batteries compared to single SPEs and ICEs. However, there are many challenges to overcome before the practical application of SCEs, including the low ionic conductivity less than 10-3 S cm-1 at ambient temperature, poor interfacial stability, and high interfacial resistance, which greatly restrict the room temperature performance. Herein, the advances of SCEs applied in all-solid-state lithium batteries are presented, including the Li ion migration mechanism of SCEs, the strategies to enhance the ionic conductivity of SCEs by various morphologies of ICEs, and construction methods of the low resistance and stable interfaces of SCEs with both cathode and anode. Finally, some typical applications of SCEs in lithium batteries are summarized and future development directions are prospected. This work presents how it is quite significant to further enhance the ionic conductivity of SCEs by developing the novel SPEs with the special morphology of ICEs for advanced all-solid-state lithium batteries.

https://onlinelibrary.wiley.com/doi/epdf/10.1002/advs.201903088

Progress and Perspective of Ceramic/Polymer Composite Solid Electrolytes for Lithium Batteries

Safety is the most important requirement for autonomous vehicles; hence, the ultimate challenge of designing an edge computing ecosystem for autonomous vehicles is to deliver enough computing power, redundancy, and security so as to guarantee the safety of autonomous vehicles. Specifically, autonomous driving systems are extremely complex; they tightly integrate many technologies, including sensing, localization, perception, decision making, as well as the smooth interactions with cloud platforms for high-definition (HD) map generation and data storage. These complexities impose numerous challenges for the design of autonomous driving edge computing systems. First, edge computing systems for autonomous driving need to process an enormous amount of data in real time, and often the incoming data from different sensors are highly heterogeneous. Since autonomous driving edge computing systems are mobile, they often have very strict energy consumption restrictions. Thus, it is imperative to deliver sufficient computing power with reasonable energy consumption, to guarantee the safety of autonomous vehicles, even at high speed. Second, in addition to the edge system design, vehicle-to-everything (V2X) provides redundancy for autonomous driving workloads and alleviates stringent performance and energy constraints on the edge side. With V2X, more research is required to define how vehicles cooperate with each other and the infrastructure. Last, safety cannot be guaranteed when security is compromised. Thus, protecting autonomous driving edge computing systems against attacks at different layers of the sensing and computing stack is of paramount concern. In this paper, we review state-of-the-art approaches in these areas as well as explore potential solutions to address these challenges.

Edge Computing for Autonomous Driving: Opportunities and Challenges

Hydrogen atom makes graphene magnetic Graphene has many extraordinary mechanical and electronic properties, but it's not magnetic. To make it so, the simplest strategy is to modify its electronic structure to create unpaired electrons. Researchers can do that by, for example, removing individual carbon atoms or adsorbing hydrogen onto graphene. This has to be done in a very controlled way because of a peculiarity of the graphene's crystal lattice, which consists of two sublattices. Gonzales-Herrero et al. deposited a single hydrogen atom on top of graphene and used scanning tunneling microscopy to detect magnetism on the sublattice lacking the deposited atom (see the Perspective by Hollen and Gupta). Science, this issue p. 437; see also p. 415 Scanning tunneling microscopy shows that a hydrogen atom deposited on graphene makes the complementary sublattice magnetic. [Also see Perspective by Hollen and Gupta] Isolated hydrogen atoms absorbed on graphene are predicted to induce magnetic moments. Here we demonstrate that the adsorption of a single hydrogen atom on graphene induces a magnetic moment characterized by a ~20–millielectron volt spin-split state at the Fermi energy. Our scanning tunneling microscopy (STM) experiments, complemented by first-principles calculations, show that such a spin-polarized state is essentially localized on the carbon sublattice opposite to the one where the hydrogen atom is chemisorbed. This atomically modulated spin texture, which extends several nanometers away from the hydrogen atom, drives the direct coupling between the magnetic moments at unusually long distances. By using the STM tip to manipulate hydrogen atoms with atomic precision, it is possible to tailor the magnetism of selected graphene regions.

/pdf/atomic-scale-control-of-graphene-magnetism-by-using-hydrogen-53d9rq6gri.pdf

Atomic-scale control of graphene magnetism by using hydrogen atoms

Highly flexible, mechanically strengthened metallic glass-based composite electrode with enhanced capacitance and cyclic stability

The current trend of Dynamic Voltage and Frequency Scaling (DVFS) techniques involve algorithms that predict when a processor is in a period of accessing off chip memory and dial down its voltage/frequency during this phase in order to reduce energy consumption with minimal, if any, effect on execution time. These algorithms often operate with a parameter that defines the tolerable performance degradation, because the various operating frequencies that a processor can be set to are often limited. This limit makes it practically impossible to dial down a processor's frequency to the exact optimal frequency that will provide maximal energy efficiency but not affect performance. This leads to a need for these algorithms to include the previously stated parameter to identify cases where choices which degrade performance to an unacceptable level and/or without providing a benefit in energy consumption are avoided. However, the overhead costs incurred by the process of voltage and frequency scaling must also be taken into consideration. We propose a study to determine the impact of these overhead costs on the overall benefit of dynamic voltage and frequency scaling.

/pdf/a-manual-approach-and-analysis-of-voltage-and-frequency-khz1u043dp.pdf

A manual approach and analysis of Voltage and Frequency Scaling using SCC

The computer industry is moving towards two extremes: extremely high-performance high-throughput cloud computing, and low-power mobile computing. Cloud computing, while providing high performance, is very costly. Google and Microsoft Bing spend billions of dollars each year to maintain their server farms, mainly due to the high power bills. On the other hand, mobile computing is under a very tight energy budget, but yet the end users demand ever increasing performance on these devices. This trend indicates that conventional architectures are not able to deliver high-performance and low power consumption at the same time, and we need a new architecture model to address the needs of both extremes. In this paper, we thus introduce our Extremely Heterogeneous Architecture (EHA) project: EHA is a novel architecture that incorporates both general-purpose and specialized cores on the same chip. The general-purpose cores take care of generic control and computation. On the other hand, the specialized cores, including GPU, hard accelerators (ASIC accelerators), and soft accelerators (FPGAs), are designed for accelerating frequently used or heavy weight applications. When acceleration is not needed, the specialized cores are turned off to reduce power consumption. We demonstrate that EHA is able to improve performance through acceleration, and at the same time reduce power consumption. Since EHA is a heterogeneous architecture, it is suitable for accelerating heterogeneous workloads on the same chip. For example, data centers and clouds provide many services, including media streaming, searching, indexing, scientific computations. The ultimate goal of the EHA project is two-fold: first, to design a chip that is able to run different cloud services on it, and through this design, we would be able to greatly reduce the cost, both recurring and non-recurring, of data centers\clouds; second, to design a light-weight EHA that runs on mobile devices, providing end users with improved experience even under tight battery budget constraints.

Introducing the extremely heterogeneous architecture

Multi-heterostructured SnO2/SnSx embedded in carbon framework for high-performance sodium-ion storage.

Abstract The microtubule (MT) plus-end binding protein Clip170 is associated closely with breast cancer invasion and migration. In this study, Clip170 tension observed by a newly designed cpstFRET tension probe was suggested to be positive related to breast cancer aggressiveness, which could be regulated by α-tubulin detyrosination-induced MT disassembly. Clip170 phosphorylation induced by Ribosomal protein S6 kinase (RSK) could also increase its tension and promote the conversion of a discrete comet-like Clip-170 distribution into a spotty pattern during cancer metastasis. Heightened Clip170 tension was correlated with the formation of cortactin-associated filopodia and lamellipodia, and then promoted invasion and metastasis both in vitro and in vivo. Meanwhile, Clip170 tension enhanced at the leading edge in directional migration, accompanying with IQGAP1 subcellular distribution variation. Our work indicates that the malignancy and directionality during breast cancer migration depend on the magnitude and polarization of Clip170 tension, and we suggest Clip170 tension as a new potential drug target for breast cancer therapy. 

https://www.nature.com/articles/s41419-022-05306-6.pdf

Chen Liu

Papers

Highly flexible, mechanically strengthened metallic glass-based composite electrode with enhanced capacitance and cyclic stability

A manual approach and analysis of Voltage and Frequency Scaling using SCC

Introducing the extremely heterogeneous architecture

Multi-heterostructured SnO2/SnSx embedded in carbon framework for high-performance sodium-ion storage.

Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration