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Chenge Li
Researcher at École Normale Supérieure
Publications - 16
Citations - 335
Chenge Li is an academic researcher from École Normale Supérieure. The author has contributed to research in topics: Live cell imaging & Protein tag. The author has an hindex of 8, co-authored 16 publications receiving 229 citations. Previous affiliations of Chenge Li include Shanghai Jiao Tong University & Centre national de la recherche scientifique.
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Journal ArticleDOI
Dynamic multicolor protein labeling in living cells.
Chenge Li,Chenge Li,Marie-Aude Plamont,Marie-Aude Plamont,Hanna L. Sladitschek,Vanessa Rodrigues,Vanessa Rodrigues,Isabelle Aujard,Isabelle Aujard,Pierre Neveu,Thomas Le Saux,Thomas Le Saux,Ludovic Jullien,Ludovic Jullien,Arnaud Gautier,Arnaud Gautier +15 more
TL;DR: Engineered fluorogenic dyes enable the dynamic switching of the fluorescence color of Fluorescence-Activating and absorption-Shifting Tag (FAST).
Journal ArticleDOI
Fluorogenic Labeling Strategies for Biological Imaging
TL;DR: This review presents a brief overview of recent labeling strategies that permits one to make protein and RNA strongly fluorescent using synthetic fluorogenic probes, and allows the development of sophisticated imaging assays, and open exciting prospects for advanced imaging, particularly for multiplexed imaging and super-resolution microscopy.
Journal ArticleDOI
The inducible chemical-genetic fluorescent marker FAST outperforms classical fluorescent proteins in the quantitative reporting of bacterial biofilm dynamics.
Amaury Monmeyran,Philippe Thomen,Philippe Thomen,Hugo Jonquière,Franck Sureau,Chenge Li,Marie-Aude Plamont,Carine Douarche,Jean-François Casella,Arnaud Gautier,Nelly Henry +10 more
TL;DR: This paper compared the ability of FAST to report on biofilm growth with that of GFP and mCherry, and demonstrated the superiority of the FAST:fluorogen probes for investigating dynamics in the complex environment of a living biofilm.
Journal ArticleDOI
Light-Activated Proteolysis for the Spatiotemporal Control of Proteins
Quentin Delacour,Quentin Delacour,Quentin Delacour,Chenge Li,Chenge Li,Chenge Li,Marie-Aude Plamont,Marie-Aude Plamont,Marie-Aude Plamont,Emmanuelle Billon-Denis,Emmanuelle Billon-Denis,Emmanuelle Billon-Denis,Isabelle Aujard,Isabelle Aujard,Isabelle Aujard,Thomas Le Saux,Thomas Le Saux,Thomas Le Saux,Ludovic Jullien,Ludovic Jullien,Ludovic Jullien,Arnaud Gautier,Arnaud Gautier,Arnaud Gautier +23 more
TL;DR: This work developed a photoactivatable auxin that acts as a photoActivatable inducer of degradation that relies on the auxin-inducible degradation system obtained by transposing components of the plant Auxin-dependent degradation pathway in mammalian cells.
Journal ArticleDOI
Fluorogenic Probing of Membrane Protein Trafficking.
Chenge Li,Aurélien Mourton,Marie-Aude Plamont,Vanessa Rodrigues,Isabelle Aujard,Michel Volovitch,Michel Volovitch,Thomas Le Saux,Franck Perez,Sophie Vriz,Sophie Vriz,Ludovic Jullien,Alain Joliot,Arnaud Gautier +13 more
TL;DR: This work presents an efficient strategy for the rapid and selective fluorescent labeling of membrane proteins based on the chemical-genetic fluorescent marker FAST (fluorescence-activating and absorption-shifting tag) and opens exciting prospects for the high-throughput screening of small molecules able to restore disease-related trafficking defects.