C
Chengyan Zhao
Researcher at National Institutes of Health
Publications - 1
Citations - 590
Chengyan Zhao is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Extracellular matrix & Biglycan. The author has an hindex of 1, co-authored 1 publications receiving 568 citations.
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Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice
T. Xu,Paolo Bianco,Paolo Bianco,Larry W. Fisher,Glenn Longenecker,Erica Smith,Steven A. Goldstein,Jeffrey Bonadio,Adele L. Boskey,Anne-Marie Heegaard,Beatrice Sommer,Kazuhito Satomura,Pedro Domínguez,Chengyan Zhao,Ashok B. Kulkarni,Pamela Gehron Robey,Marian F. Young +16 more
TL;DR: This is the first report in which deficiency of a non-collagenous ECM protein leads to a skeletal phenotype that is marked by low bone mass that becomes more obvious with age and may serve as an animal model to study the role of ECM proteins in osteoporosis.