C
Cheol Won Park
Researcher at Harvard University
Publications - 3
Citations - 5311
Cheol Won Park is an academic researcher from Harvard University. The author has contributed to research in topics: Nuclear receptor & Thyroid hormone receptor. The author has an hindex of 3, co-authored 3 publications receiving 5010 citations. Previous affiliations of Cheol Won Park include Howard Hughes Medical Institute.
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Journal ArticleDOI
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
Pere Puigserver,Zhidan Wu,Cheol Won Park,Reed A. Graves,Margaret E. Wright,Bruce M. Spiegelman +5 more
TL;DR: Results indicate that PGC-1 plays a key role in linking nuclear receptors to the transcriptional program of adaptive thermogenesis.
Journal ArticleDOI
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
Michael Ohh,Cheol Won Park,Cheol Won Park,Mircea Ivan,Michael A. Hoffman,Tae-You Kim,Tae-You Kim,L. Eric Huang,Nikola P. Pavletich,Nikola P. Pavletich,Vincent Chau,William G. Kaelin,William G. Kaelin +12 more
TL;DR: It is shown that pVHL, through its β-domain, binds directly to hypoxia-inducible factor (HIF), thereby targeting HIF for ubiquitination in an α-domain-dependent manner, the first function to be ascribed to the pV HL β- domain.
Journal ArticleDOI
An adipogenic cofactor bound by the differentiation domain of PPARγ
Gonzalo Castillo,Regina P. Brun,Jennifer K. Rosenfield,Stefanie Hauser,Cheol Won Park,Amy E Troy,Margaret E. Wright,Bruce M. Spiegelman +7 more
TL;DR: Interactions between PGC‐2, a receptor isoform‐selective cofactor and PPARγ contribute to the adipogenic action of this receptor, which induces adipogenesis and increases insulin sensitivity.