Cherie L. Ramirez

TL;DR: In the version of this correspondence initially published, the two previously published datasets analyzed were labeled with incorrect references in Figure 1b.

TL;DR: An energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage is established and strategies for the improvement of future ZFN design are suggested.

TL;DR: Together, these data suggest that BRD–NUT fusion proteins contribute to carcinogenesis by associating with chromatin and interfering with epithelial differentiation.

TL;DR: In this article, a synthetic framework for systematically constructing eukaryotic transcription functions using artificial zinc fingers, modular DNA-binding domains found within many eUKaryotic TFs, is presented.

TL;DR: The generation of iPSC lines from sickle cell anemia patients and in situ correction of the disease causing mutation using three ZFN pairs made by the publicly available oligomerized pool engineering method (OPEN) provide an important proof of principle that ZFNs can be used to produce gene‐corrected human iPSCs that could be used for therapeutic applications.