C
Chihiro Sugimoto
Researcher at Hokkaido University
Publications - 328
Citations - 8593
Chihiro Sugimoto is an academic researcher from Hokkaido University. The author has contributed to research in topics: Theileria & Gene. The author has an hindex of 47, co-authored 325 publications receiving 7737 citations. Previous affiliations of Chihiro Sugimoto include University of Zambia & Obihiro University of Agriculture and Veterinary Medicine.
Papers
More filters
Journal ArticleDOI
Loop-Mediated Isothermal Amplification for Detection of African Trypanosomes
Noritaka Kuboki,Noboru Inoue,Tatsuya Sakurai,Francescopaolo Di Cello,Dennis J. Grab,Hiroshi Suzuki,Chihiro Sugimoto,Ikuo Igarashi +7 more
TL;DR: The conditions for a highly sensitive, specific, and easy diagnostic assay based on LAMP technology for the detection of parasites in the Trypanosoma brucei group are reported, showing that the sensitivity of the LAMP-based method for detection of trypanosomes in vitro is up to 100 times higher than that of PCR-based methods.
Journal ArticleDOI
Evolution and genetic diversity of Theileria.
TL;DR: The outline of the evolution of Theileria, which includes T. orientalis, is provided, and the possible mechanisms generating genetic diversity among parasite populations are discussed, to discuss the potential implications of a genetically diverse parasite population in the context of TheILeria vaccine development.
Journal ArticleDOI
Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks.
TL;DR: Nucleotide sequencing of SSU rRNA and MPSP genes revealed the presence of four Theileria genotypes, with the occurrence of ikeda and type 4 (type C) previously not reported to occur and silent mutation is thought to have enhanced parasite evasion of the host immune response causing the outbreak.
Journal ArticleDOI
Species-specific loop-mediated isothermal amplification (LAMP) for diagnosis of trypanosomosis.
Oriel M. M. Thekisoe,Noritaka Kuboki,Andrew Nambota,Kozo Fujisaki,Chihiro Sugimoto,Ikuo Igarashi,Jun Yasuda,Noboru Inoue +7 more
TL;DR: Loop-mediated isothermal amplification (LAMP) is a rapid and simple technique since it can be carried out in 1 h and requires only a simple heating device for incubation, which has great potential of being used for diagnosis of trypanosomosis in the laboratory and the field.
Journal ArticleDOI
Identification of a novel gene, dep, associated with depolymerization of the capsular polymer in Bacillus anthracis.
Ikuo Uchida,Sou-ichi Makino,Chihiro Sasakawa,Masanosuke Yoshikawa,Chihiro Sugimoto,Nobuyuki Terakado +5 more
TL;DR: Although the biological functions of the dep gene are unknown, it is possible that low‐molecular‐weight, diffusible polyglutamates produced through the action of the Dep gene may act to inhibit host defence mechanisms.