C
Chikako Murakami
Researcher at Kobe Gakuin University
Publications - 23
Citations - 632
Chikako Murakami is an academic researcher from Kobe Gakuin University. The author has contributed to research in topics: DNA polymerase & Polymerase. The author has an hindex of 14, co-authored 23 publications receiving 604 citations. Previous affiliations of Chikako Murakami include Osaka Prefecture University.
Papers
More filters
Journal ArticleDOI
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos
Yoshiyuki Mizushina,Toshihiro Akihisa,Motohiko Ukiya,Chikako Murakami,Isoko Kuriyama,Xianai Xu,Hiromi Yoshida,Kengo Sakaguchi +7 more
TL;DR: Findings suggest that dehydroebriconic acid and dehydrotrametenonic acid should be designated as topo II‐preferential inhibitors, although they also moderately inhibited all the mammalian DNA polymerases tested.
Journal ArticleDOI
Effects of glycolipids from spinach on mammalian DNA polymerases.
Chikako Murakami,Taeko Kumagai,Takahiko Hada,Ui Kanekazu,Satoshi Nakazawa,Shinji Kamisuki,Naoki Maeda,Xianai Xu,Hiromi Yoshida,Fumio Sugawara,Kengo Sakaguchi,Yoshiyuki Mizushina +11 more
TL;DR: Both MGDG and MGMG could halt the cell cycle at the G1 phase, and subsequently induced severe apoptosis, and the relationship between the DNA polymerase inhibition and the cell growth effect by these glycolipids is discussed.
Journal ArticleDOI
Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells.
TL;DR: EGCG and EGC protected the depletion of α-tocopherol in the cells, and the glutathione content was enhanced by all four catechins.
Journal ArticleDOI
Pseudodeflectusin, a novel isochroman derivative from Aspergillus pseudodeflectus a parasite of the sea weed, Sargassum fusiform, as a selective human cancer cytotoxin.
Akitsu Ogawa,Chikako Murakami,Shinji Kamisuki,Isoko Kuriyama,Hiromi Yoshida,Fumio Sugawara,Yoshiyuki Mizushina +6 more
TL;DR: This compound exhibited cytotoxicity for several human cancer cell lines from the stomach, cervix, and peripheral blood, but did not affect those from the lung, colon, or colon.
Journal ArticleDOI
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Chikako Murakami,Masaharu Takemura,Yuichi Sugiyama,Shinji Kamisuki,Hitomi Asahara,Miho Kawasaki,Tomomi Ishidoh,Stuart Linn,Shonen Yoshida,Fumio Sugawara,Hiromi Yoshida,Kengo Sakaguchi,Yoshiyuki Mizushina +12 more
TL;DR: RAL and RA should be called selective inhibitors of mammalian DNA polymerase including telomerase, and RAL was a specific inhibitor of mammalian replicative DNA polymerases.