Chiraz El-Aouni

TL;DR: The findings show that short-term cardioprotection derived by regional application of eEPCs can be attributed, at least in part, to Tβ4.

TL;DR: Investigation of the ability of cardiotropic adeno-associated viral vector (AAV2.9) to induce prolonged expression of vascular endothelial growth factor (VEGF)-A and platelet-derived growthFactor (PDGF)-B in a rabbit hindlimb ischemia model and a pig model of hibernating myocardium found that rAAV improves regional and global myocardial function in hibernatile myocardia.

TL;DR: Whereas HO-1 deficiency exacerbates post-ischemic cardiac inflammation in mice, hHO-1 gene therapy attenuates inflammation after ischemia and reperfusion in murine and porcine hearts.

TL;DR: It is concluded that NF κB activation by LL37 or transient p65‐transfection increases functionally relevant eEPC recruitment to ischemic muscle tissue via induction of PSGL‐1 and E‐selectin.

TL;DR: In this article, selective pressure-regulated retroinfusion of the great cardiac vein was performed at day 28 for regional delivery of either saline or empty vector or Ad2/Hif-1α/VP16.