M
Maike Knorr
Researcher at University of Mainz
Publications - 56
Citations - 3018
Maike Knorr is an academic researcher from University of Mainz. The author has contributed to research in topics: Endothelial dysfunction & Angiotensin II. The author has an hindex of 24, co-authored 53 publications receiving 2387 citations.
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Journal ArticleDOI
Lysozyme M–Positive Monocytes Mediate Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction
Philip Wenzel,Maike Knorr,Sabine Kossmann,Jan Stratmann,Michael Hausding,Swenja Schuhmacher,Susanne Karbach,Melanie Schwenk,Nir Yogev,Eberhard Schulz,Matthias Oelze,Stephan Grabbe,Helmut Jonuleit,Christian Becker,Andreas Daiber,Ari Waisman,Thomas Münzel +16 more
TL;DR: Infiltrating monocytes with a proinflammatory phenotype and macrophages rather than neutrophils appear to be essential for ATII-induced vascular dysfunction and arterial hypertension.
Journal ArticleDOI
Gut Microbiota Promote Angiotensin II–Induced Arterial Hypertension and Vascular Dysfunction
Susanne Karbach,Tanja Schönfelder,Inês Brandão,Eivor Wilms,Nives Hörmann,Sven Jäckel,Rebecca Schüler,Stefanie Finger,Maike Knorr,Jeremy Lagrange,Moritz Brandt,Ari Waisman,Sabine Kossmann,Katrin Schäfer,Thomas Münzel,Christoph Reinhardt,Philip Wenzel +16 more
TL;DR: Gut microbiota facilitate AngII‐induced vascular dysfunction and hypertension, at least in part, by supporting an MCP‐1/IL‐17 driven vascular immune cell infiltration and inflammation.
Journal ArticleDOI
Long-Term Prognosis of Patients With Takotsubo Syndrome
Jelena-R. Ghadri,Ken Kato,Victoria L. Cammann,Sebastiano Gili,Stjepan Jurisic,Davide Di Vece,Alessandro Candreva,Katharina J. Ding,Jozef Micek,Konrad A. Szawan,Beatrice Bacchi,Rahel Bianchi,Rena A. Levinson,Manfred Wischnewsky,Burkhardt Seifert,Susanne A. Schlossbauer,Rodolfo Citro,Eduardo Bossone,Thomas Münzel,Maike Knorr,Susanne Heiner,Fabrizio D'Ascenzo,Jennifer Franke,Annahita Sarcon,L. Christian Napp,Miłosz Jaguszewski,Michel Noutsias,Hugo A. Katus,Christof Burgdorf,Heribert Schunkert,Holger Thiele,Johann Bauersachs,Carsten Tschöpe,Burkert Pieske,Lawrence Rajan,Guido Michels,Roman Pfister,Alessandro Cuneo,Claudius Jacobshagen,Gerd Hasenfuß,Mahir Karakas,Wolfgang Koenig,Wolfgang Rottbauer,Samir M. Said,Ruediger C. Braun-Dullaeus,Adrian P. Banning,Florim Cuculi,Richard Kobza,Thomas Fischer,Tuija Vasankari,K.E. Juhani Airaksinen,Grzegorz Opolski,Rafal Dworakowski,Philip MacCarthy,Christoph Kaiser,Stefan Osswald,Leonarda Galiuto,Filippo Crea,Wolfgang Dichtl,Klaus Empen,Stephan B. Felix,Clément Delmas,Olivier Lairez,Ibrahim El-Battrawy,Ibrahim Akin,Martin Borggrefe,John D. Horowitz,Martin Kozel,Petr Tousek,Petr Widimský,Ekaterina Gilyarova,Alexandra Shilova,Mikhail Gilyarov,David E. Winchester,Christian Ukena,Jeroen J. Bax,Abhiram Prasad,Michael Böhm,Thomas F. Lüscher,Frank Ruschitzka,Christian Templin +80 more
TL;DR: It is demonstrated that TTS can either be benign or a life-threating condition depending on the inciting stress factor, and a new classification based on triggers is proposed, which can serve as a clinical tool to predict short- and long-term outcomes of TTS.
Journal ArticleDOI
Interleukin 17 Drives Vascular Inflammation, Endothelial Dysfunction, and Arterial Hypertension in Psoriasis-Like Skin Disease
Susanne Karbach,Andrew L. Croxford,Matthias Oelze,Rebecca Schüler,Daniel Minwegen,Joanna Wegner,Lija Koukes,Nir Yogev,Alexei Nikolaev,Sonja Reißig,Alexander Ullmann,Maike Knorr,Maximilian J. Waldner,Markus F. Neurath,Huige Li,Zhixiong Wu,Christoph Brochhausen,Jürgen Scheller,Stefan Rose-John,Carolin Piotrowski,Ingo Bechmann,Markus P. Radsak,Philipp S. Wild,Andreas Daiber,Esther von Stebut,Philip Wenzel,Ari Waisman,Thomas Münzel +27 more
TL;DR: Dermal overexpression of IL-17A induces systemic endothelial dysfunction, vascular oxidative stress, arterial hypertension, and increases mortality mainly driven by myeloperoxidase+CD11b+GR1+F4/80− inflammatory cells.
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Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1—evidence for direct and indirect antioxidant actions of bilirubin
Thomas Jansen,Marcus Hortmann,Matthias Oelze,Benjamin Opitz,Sebastian Steven,Richard Schell,Maike Knorr,Susanne Karbach,Swenja Schuhmacher,Philip Wenzel,Thomas Münzel,Andreas Daiber +11 more
TL;DR: Since bilirubin significantly scavenged RONS but chronic treatment was even more protective the authors' observations support direct and indirect antioxidant properties of BVR and bilirUBin and an important role for B VR and bilIRubin in HO-1 conferred protection of endothelial cells.