C
Choong-Gu Lee
Researcher at Korea Institute of Science and Technology
Publications - 32
Citations - 1912
Choong-Gu Lee is an academic researcher from Korea Institute of Science and Technology. The author has contributed to research in topics: Immune system & T cell. The author has an hindex of 18, co-authored 31 publications receiving 1558 citations. Previous affiliations of Choong-Gu Lee include Gwangju Institute of Science and Technology & Chosun University.
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Journal ArticleDOI
Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders
Ho Keun Kwon,Choong-Gu Lee,Jae-Seon So,Chang-Suk Chae,Ji Sun Hwang,Anupama Sahoo,Jong Hee Nam,Joon Haeng Rhee,Ki-Chul Hwang,Sin-Hyeog Im +9 more
TL;DR: The therapeutical effect of the probiotics is associated with enrichment of CD4+Foxp3+ Tregs in the inflamed regions and represents an applicable treatment of inflammatory immune disorders.
Journal ArticleDOI
Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1
Ho Keun Kwon,Ji-Sun Hwang,Jae-Seon So,Choong-Gu Lee,Anupama Sahoo,Jae-Ha Ryu,Won Kyung Jeon,Byoung Seob Ko,Chang-Rok Im,Sung Haeng Lee,Zee Yong Park,Sin-Hyeog Im +11 more
TL;DR: This study suggests that anti-tumor effect of cinnamon extracts is directly linked with enhanced pro-apoptotic activity and inhibition of NFκB and AP1 activities and their target genes in vitro and in vivo mouse melanoma model.
Journal ArticleDOI
Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions
Jae-Seon So,Ho Keun Kwon,Choong-Gu Lee,Hwa-Jung Yi,Jin-A Park,Soyeon Lim,Ki-Chul Hwang,Young Ho Jeon,Sin-Hyeog Im +8 more
TL;DR: Oral administration of L. casei protects against rheumatoid arthritis progression by investigating the effector functions of CD4(+) T cells and suppresses the type II collagen-reactive effector function of Th1-type cellular and humoral immune responses in arthritic inflammation.
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Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cells
Ravi Verma,Changhon Lee,Eun-Ji Jeun,Jaeu Yi,Kwang Soon Kim,Ambarnil Ghosh,Seohyun Byun,Choong-Gu Lee,Hye-Ji Kang,Gi-Cheon Kim,Chang-Duk Jun,Gwenaël Jan,Chang-Hee Suh,Ju-Yang Jung,Jonathan Sprent,Jonathan Sprent,Dipayan Rudra,Cristina De Castro,Antonio Molinaro,Charles D. Surh,Sin-Hyeog Im +20 more
TL;DR: Bifidobacterium bifidum is defined as a potent inducer of Foxp3+ Treg cells with diverse T cell receptor specificity to dietary antigens, commensal bacteria, and B. bifodum itself, and CSGG is identified as a functional component of Treg-inducing bacteria, highlighting the immunomodulatory potential of CSGG and CS GG-producing microbes.
Journal ArticleDOI
Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells.
Ho Keun Kwon,Won Kyung Jeon,Ji-Sun Hwang,Choong-Gu Lee,Jae-Seon So,Jin-A Park,Byoung Seob Ko,Sin-Hyeog Im +7 more
TL;DR: In vitro and in vivo system, cinnamon treatment strongly inhibited the expression of pro-angiogenic factors and master regulators of tumor progression not only in melanoma cell lines but also in experimental melanoma model.