Hye-Ji Kang

TL;DR: Bifidobacterium bifidum is defined as a potent inducer of Foxp3+ Treg cells with diverse T cell receptor specificity to dietary antigens, commensal bacteria, and B. bifodum itself, and CSGG is identified as a functional component of Treg-inducing bacteria, highlighting the immunomodulatory potential of CSGG and CS GG-producing microbes.

TL;DR: In this paper, the authors review selection methods for immunomodulatory probiotic strains and the mechanism of action of probiotics in immune modulation and identify functional probiotic with specific immune regulatory property.

TL;DR: Kim et al. show that Ets1 deletion in T cells, but not B cells or DCs, result in SLE‐like humoral autoimmunity, which was due to the expansion of GATA‐3+Bcl6+ Tfh2 cells and could be alleviated by neutralizing IL‐4.

TL;DR: It is demonstrated that emodin significantly improved the anti-cancer effect of sorafenib in HCC cells, such as HepG2, Hep3B, Huh7, SK-HEP-1, and PLC/PRF5, and it is suggested that the combination of emod in and sorafENib may offer a potential therapy for patients with advanced HCC.

TL;DR: Investigation of the safety and probiotic properties of 18 L. plantarum strains isolated from fermented food products, green tea, and insects suggests they can be considered as potential beneficial strains for human and animal applications.