抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

“Bioinformatics” 특집을 내면서

1980 Preface * 1999 Preface * 1999 Acknowledgements * Introduction * 1 Circular Logic * 2 Phase Singularities (Screwy Results of Circular Logic) * 3 The Rules of the Ring * 4 Ring Populations * 5 Getting Off the Ring * 6 Attracting Cycles and Isochrons * 7 Measuring the Trajectories of a Circadian Clock * 8 Populations of Attractor Cycle Oscillators * 9 Excitable Kinetics and Excitable Media * 10 The Varieties of Phaseless Experience: In Which the Geometrical Orderliness of Rhythmic Organization Breaks Down in Diverse Ways * 11 The Firefly Machine 12 Energy Metabolism in Cells * 13 The Malonic Acid Reagent ('Sodium Geometrate') * 14 Electrical Rhythmicity and Excitability in Cell Membranes * 15 The Aggregation of Slime Mold Amoebae * 16 Numerical Organizing Centers * 17 Electrical Singular Filaments in the Heart Wall * 18 Pattern Formation in the Fungi * 19 Circadian Rhythms in General * 20 The Circadian Clocks of Insect Eclosion * 21 The Flower of Kalanchoe * 22 The Cell Mitotic Cycle * 23 The Female Cycle * References * Index of Names * Index of Subjects

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/596B270197FE27DE5FABB598B6210622/S0025557200150892a.pdf/div-class-title-span-class-italic-the-geometry-of-biological-time-span-by-a-t-winfree-pp-544-dm68-corrected-second-printing-1990-isbn-3-540-52528-9-springer-div.pdf

The geometry of biological time , by A. T. Winfree. Pp 544. DM68. Corrected Second Printing 1990. ISBN 3-540-52528-9 (Springer)

Complex networks arise in a wide range of biological and sociotechnical systems. Epidemic spreading is central to our understanding of dynamical processes in complex networks, and is of interest to physicists, mathematicians, epidemiologists, and computer and social scientists. This review presents the main results and paradigmatic models in infectious disease modeling and generalized social contagion processes.

Epidemic processes in complex networks

https://deim.urv.cat/~alexandre.arenas/publicacions/pdf/review.pdf

Synchronization in complex networks

Different chaos synchronization based encryption schemes are reviewed and compared from the practical point of view. As an efficient cryptanalysis tool for chaos encryption, a proposal based on the Error Function Attack is presented systematically and used to evaluate system security. We define a quantitative measure (Quality Factor) of the effective applicability of a chaos encryption scheme, which takes into account the security, the encryption speed, and the robustness against channel noise. A comparison is made of several encryption schemes and it is found that a scheme based on one-way coupled chaotic map lattices performs outstandingly well, as judged from Quality Factor.

Error Function Attack of chaos synchronization based encryption schemes

It has been proposed to realize secure communication using chaotic synchronization via transmission of a binary message encoded by parameter modulation in the chaotic system. This paper considers the use of parameter adaptive control techniques to extract the message, based on the assumptions that we know the equation form of the chaotic system in the transmitter but do not have access to the precise values of the parameters which are kept secret as a secure set. In the case in which a synchronizing system can be constructed using parameter adaptive control by the transmitted signal and the synchronization is robust to parameter mismatches, the parameter modulation can be revealed and the message decoded without resorting to exact parameter values in the secure set. A practical local Lyapunov function method for designing parameter adaptive control rules based on originally synchronized systems is presented.

Decoding information by following parameter modulation with parameter adaptive control.

Geometric phase, for a two-level atom in an electromagnetic field interacting with a squeezed-vacuum reservoir, is calculated by establishing connecting density matrices, describing an evolution of a quantum open system, with a nonunit vector ray in a complex projective Hilbert space. Because the geometric phase depends only on the smooth curve on this space, it is formulated entirely in terms of geometric structures. The results show that the geometric phase for the squeezed-vacuum reservoir has fully different behavior in comparison with one for the normal vacuum reservoir.

Effects of a squeezed-vacuum reservoir on geometric phase

The synchronization of two different chaotic oscillators is studied, based on an open-loop control – the entrainment control. We consider two types of synchronization: complete synchronization and effectively complete synchronization. The sufficient conditions that two different systems can be synchronized by this method is discussed. Furthermore, a hierarchical idea to synchronize multiple chaotic subsystems is proposed.

On the synchronization of different chaotic oscillators

A mapping is established in connecting density matrices, associated with an evolution of a quantum open system, with vector ray in a complex projective Hilbert space. By using the corresponding vector ray to represent the open two-level system, we may observe the geometric phase for the open two-level system. The geometric phase of the open two-level system depends only on the smooth (open or closed) curve in the complex projective Hilbert space of ray, which is formulated entirely in terms of geometric structures on this space.

http://iopscience.iop.org/article/10.1209/epl/i2006-10057-1/pdf

Choy Heng Lai

Papers

Error Function Attack of chaos synchronization based encryption schemes

Decoding information by following parameter modulation with parameter adaptive control.

Effects of a squeezed-vacuum reservoir on geometric phase

On the synchronization of different chaotic oscillators

Geometric phase in open two-level system