C
Chris J. McGee
Researcher at Wellcome Trust Sanger Institute
Publications - 2
Citations - 736
Chris J. McGee is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Genome-wide association study & IRF8. The author has an hindex of 2, co-authored 2 publications receiving 623 citations.
Papers
More filters
Journal ArticleDOI
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Benjamin P. Fairfax,Peter Humburg,Seiko Makino,Vivek Naranbhai,Daniel Wong,Evelyn Lau,Luke Jostins,Katharine Plant,Robert Andrews,Chris J. McGee,Julian C. Knight +10 more
TL;DR: This work mapped interindividual variation in gene expression as a quantitative trait, defining expression quantitative trait loci (eQTLs) and found trans associations to the major histocompatibility complex are dependent on context, paralleling the expression of class II genes.
Journal ArticleDOI
Characterization of the yehUT Two-Component Regulatory System of Salmonella enterica Serovar Typhi and Typhimurium
Vanessa K. Wong,Derek Pickard,Lars Barquist,Karthikeyan Sivaraman,Andrew J. Page,Peter J. Hart,Mark J. Arends,Kathryn E. Holt,Leanne Kane,Lynda Mottram,Louise Ellison,Ruben Bautista,Chris J. McGee,Sally Kay,Thomas Wileman,Linda J. Kenney,Calman A. MacLennan,Robert A. Kingsley,Gordon Dougan +18 more
TL;DR: Growth, metabolic and antimicrobial susceptibility tests identified no obvious influences of yehUT on these phenotypes and deletion had no detectable effect on the ability of these mutant Salmonella to invade cultured epithelial cells.