C
Christian J. Wiedermann
Researcher at University of Innsbruck
Publications - 156
Citations - 9058
Christian J. Wiedermann is an academic researcher from University of Innsbruck. The author has contributed to research in topics: Chemotaxis & Receptor. The author has an hindex of 52, co-authored 156 publications receiving 8670 citations. Previous affiliations of Christian J. Wiedermann include Saga Group.
Papers
More filters
Journal ArticleDOI
Toll-like Receptor 4 Polymorphisms and Atherogenesis
Stefan Kiechl,Eva Lorenz,Markus Reindl,Christian J. Wiedermann,Friedrich Oberhollenzer,Enzo Bonora,Johann Willeit,David A. Schwartz +7 more
TL;DR: The Asp299Gly TLR4 polymorphism, which attenuates receptor signaling and diminishes the inflammatory response to gram-negative pathogens, is associated with a decreased risk of atherosclerosis, consistent with the hypothesis that innate immunity may play a part in atherogenesis.
Journal ArticleDOI
Chronic Infections and the Risk of Carotid Atherosclerosis Prospective Results From a Large Population Study
Stefan Kiechl,Georg Egger,Manuel Mayr,Christian J. Wiedermann,Enzo Bonora,Friedrich Oberhollenzer,Michele Muggeo,Qingbo Xu,Georg Wick,Werner Poewe,Johann Willeit +10 more
TL;DR: Chronic infections amplified the risk of atherosclerosis development in the carotid arteries and remained independently significant after adjustment for classic vascular risk attribu...
Journal ArticleDOI
Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: Prospective results from the bruneck study
Christian J. Wiedermann,Stefan Kiechl,Stefan Dunzendorfer,Peter Schratzberger,Georg Egger,Friedrich Oberhollenzer,Johann Willeit +6 more
TL;DR: First epidemiologic evidence that endotoxemia constitutes a strong risk factor of early atherogenesis in subjects with chronic or recurrent bacterial infections and a link in the association between cigarette smoking and atherosclerotic disease is yielded.
Journal ArticleDOI
Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation.
Joachim Kienast,Mathias Juers,Christian J. Wiedermann,Johannes N. Hoffmann,Helmut Ostermann,Richard Strauss,Heinz-Otto Keinecke,Brian Warren,Steven M. Opal +8 more
TL;DR: The adapted ISTH DIC score may identify patients with severe sepsis who potentially benefit from high‐dose AT treatment, and may result in a significant mortality reduction.
Journal ArticleDOI
Oxidized Phospholipids, Lipoprotein(a), Lipoprotein-Associated Phospholipase A2 Activity, and 10-Year Cardiovascular Outcomes. Prospective Results From the Bruneck Study
Stefan Kiechl,Johann Willeit,Manuel Mayr,Brigitte Viehweider,Martin Oberhollenzer,Florian Kronenberg,Christian J. Wiedermann,Sabine Oberthaler,Qingbo Xu,Joseph L. Witztum,Sotirios Tsimikas +10 more
TL;DR: It is demonstrated that OxPL/apoB levels predict 10-year CVD event rates independently of traditional risk factors, high sensitivity C-reactive protein (hsCRP), and lipoprotein-associated phospholipase A2 (Lp-PLA2) activity.