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Christian Weyer

Researcher at Amylin Pharmaceuticals

Publications -  103
Citations -  18814

Christian Weyer is an academic researcher from Amylin Pharmaceuticals. The author has contributed to research in topics: Insulin & Pramlintide. The author has an hindex of 59, co-authored 103 publications receiving 18015 citations. Previous affiliations of Christian Weyer include National Institutes of Health.

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Journal ArticleDOI

Plasma Adiponectin Concentration Is Associated With Skeletal Muscle Insulin Receptor Tyrosine Phosphorylation, and Low Plasma Concentration Precedes a Decrease in Whole-Body Insulin Sensitivity in Humans

Norbert Stefan, +10 more
- 01 Jun 2002 - 
TL;DR: The cross-sectional data suggest a role of physiological concentration of fasting plasma adiponectin in the regulation of skeletal muscle IR tyrosine phosphorylation and indicate that adiponECTin plays an important role in regulation of insulin sensitivity in humans.
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High White Blood Cell Count Is Associated With a Worsening of Insulin Sensitivity and Predicts the Development of Type 2 Diabetes

Barbora Vozarova, +5 more
- 01 Feb 2002 - 
TL;DR: The predictive effect of WBC persisted after additional adjustment for established predictors of diabetes, consistent with the hypothesis that a chronic activation of the immune system may play a role in the pathogenesis of type 2 diabetes.
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The role of impaired early insulin secretion in the pathogenesis of Type II diabetes mellitus.

Richard E. Pratley, +1 more
- 01 Aug 2001 - 
TL;DR: Strategies that enhance early insulin secretion improve glucose tolerance and represent a novel and more physiologic approach to improving glycaemic control in patients with Type II diabetes mellitus.
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Leptin responsiveness restored by amylin agonism in diet-induced obesity: Evidence from nonclinical and clinical studies

Jonathan D. Roth, +8 more
- 20 May 2008 - 
TL;DR: Findings provide both nonclinical and clinical evidence that amylin agonism restored leptin responsiveness in diet-induced obesity, suggesting that integrated neurohormonal approaches to obesity pharmacotherapy may facilitate greater weight loss by harnessing naturally occurring synergies.
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Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development.

Christian Weyer, +3 more
- 01 Jan 2001 - 
TL;DR: During each stage of the development of type 2 diabetes, insulin resistance and insulin secretory dysfunction are independent predictors of worsening glucose tolerance and are, therefore, both targets for the primary prevention of the disease.