C
Christine Beemelmanns
Researcher at Leibniz Association
Publications - 125
Citations - 2056
Christine Beemelmanns is an academic researcher from Leibniz Association. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 23, co-authored 111 publications receiving 1459 citations. Previous affiliations of Christine Beemelmanns include RWTH Aachen University & University of Strasbourg.
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Samarium diiodide induced ketyl-(het)arene cyclisations towards novel N-heterocycles
TL;DR: This tutorial review discusses recent advances in the field of ketyl-(het)arene cyclisations promoted by samarium diiodide and related processes, and summarizes diversity orientated approaches towards nitrogen heterocycles and emphasize other approaches with SmI(2) as well as electrochemical cyclisation methods providing similar N-heterocycles.
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Bacterial lipids activate, synergize, and inhibit a developmental switch in choanoflagellates
Arielle Woznica,Alexandra M. Cantley,Christine Beemelmanns,Elizaveta Freinkman,Jon Clardy,Nicole King +5 more
TL;DR: It is revealed that multiple bacterially produced lipids converge to activate, enhance, and inhibit multicellular development in a choanoflagellate.
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A short formal total synthesis of strychnine with a samarium diiodide induced cascade reaction as the key step.
TL;DR: Treatment of indole substrates (I according to A) produces mainly the tetracyclic heterocycles (II) and (IV) in a diastereomerically pure form as scaffolds of the Strychnos alkaloids as discussed by the authors.
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Natural products from microbes associated with insects
TL;DR: It is demonstrated that the exploration of specific microbial–host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.
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Macrotermycins A–D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39
Christine Beemelmanns,Timothy R. Ramadhar,Ki-Hyun Kim,Jonathan L. Klassen,Shugeng Cao,Thomas P. Wyche,Yanpeng Hou,Michael Poulsen,Tim S. Bugni,Cameron R. Currie,Jon Clardy +10 more
TL;DR: Bioassay-guided metabolomic analyses led to the characterization of four new 20-membered glycosylated polyketide macrolactams, macrotermycins A-D, from a termite-associated actinomycete, Amycolatopsis sp.