C
Christine Ebeling
Publications - 8
Citations - 754
Christine Ebeling is an academic researcher. The author has contributed to research in topics: Scrapie & Incubation period. The author has an hindex of 7, co-authored 8 publications receiving 722 citations.
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Journal ArticleDOI
Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation
Kiyoshi Niwa,Linda H. Younkin,Christine Ebeling,Sherry Turner,David Westaway,Steven G. Younkin,Karen H. Ashe,George A. Carlson,Costantino Iadecola +8 more
TL;DR: Transgenic mice overexpressing APP and Abeta have a profound attenuation in the increase in neocortical blood flow elicited by somatosensory activation, which indicates a potentially deleterious mismatch between substrate delivery and energy demands imposed by neural activity.
Journal ArticleDOI
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
George A. Carlson,Christine Ebeling,Shu-Lian Yang,Glenn C. Telling,Marilyn Torchia,Darlene Groth,David Westaway,Stephen J. DeArmond,Stanley B. Prusiner +8 more
TL;DR: The results suggest that scrapie "strain-specific" incubation times can be explained by differences in the relative efficiency of allotypic interactions that lead to conversion of PrPC into PrPSc.
Journal ArticleDOI
Quantitative trait loci affecting prion incubation time in mice.
Dennis A. Stephenson,Kami E. Chiotti,Christine Ebeling,Darlene Groth,Stephen J. DeArmond,Stanley B. Prusiner,George A. Carlson +6 more
TL;DR: The authors' analysis revealed loci on Chromosomes 9 and 11 that affect prion susceptibility that are involved in prion replication and determinant of susceptibility to prion disease.
Journal ArticleDOI
Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice
David Westaway,Carol Mirenda,Dallas Foster,Yeganeh Zebarjadian,Michael R. Scott,Marilyn Torchia,Shu-Lian Yang,Hana Serban,Stephen J. DeArmond,Christine Ebeling,Stanley B. Prusiner,George A. Carlson +11 more
TL;DR: In this paper, the authors analyzed the effect of the ILnJ Prn-p b allele and a distinct incubation time locus designated as PRn-i on scrapie incubation times.
Journal ArticleDOI
New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification.
Philip Babij,Martine Roudier,Tom Graves,Chun-Ya E. Han,Mark Chhoa,Chi-Ming Li,Todd Juan,Sean Morony,Mario Grisanti,Xiaodong Li,Longchuan Yu,Denise Dwyer,David Lloyd,Michael Bass,William G. Richards,Christine Ebeling,Julie Amato,George A. Carlson +17 more
TL;DR: A role for the Enpp1 gene in the pathogenesis associated with mineralization of articular cartilage and vascular calcification is supported and the utility of the chemical mutagenesis approach for identification of potential disease genes is confirmed.