C
Christine von Toerne
Researcher at Protein Sciences
Publications - 58
Citations - 1843
Christine von Toerne is an academic researcher from Protein Sciences. The author has contributed to research in topics: Hippocampus & Proteome. The author has an hindex of 21, co-authored 53 publications receiving 1362 citations. Previous affiliations of Christine von Toerne include Helmholtz Zentrum München.
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Journal ArticleDOI
The proteome of native adult Muller glial cells from murine retina
Antje Grosche,Alexandra Hauser,Marlen F. Lepper,Rebecca Mayo,Christine von Toerne,Juliane Merl-Pham,Stefanie M. Hauck +6 more
TL;DR: A novel approach to isolate intact glial cells from adult retina in combination with proteomic profiling enabled the identification of novel Müller glia specific proteins, which were validated as markers and for their functional impact in glial physiology.
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Direct comparison of MS-based label-free and SILAC quantitative proteome profiling strategies in primary retinal Müller cells
TL;DR: P phenotyped primary porcine RMGs in dependence of cultivation time using different quantitative proteomic strategies and found proteins correlated to cellular transitions and dedifferentiation were also found among the proteins only significant in one or two of the applied strategies.
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Restless Legs Syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon
Derek Spieler,Maria Kaffe,Franziska Knauf,José Bessa,Juan J. Tena,Florian Giesert,Barbara Schormair,Erik Tilch,Hyun-Ok Kate Lee,Marion Horsch,Darina Czamara,Nazanin Karbalai,Christine von Toerne,Melanie Waldenberger,Christian Gieger,Peter Lichtner,Melina Claussnitzer,Ronald Naumann,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Miguel Torres,Lillian Garrett,Jan Rozman,Martin Klingenspor,Valerie Gailus-Durner,Helmut Fuchs,Martin Hrabé de Angelis,Johannes Beckers,Sabine M. Hölter,Thomas Meitinger,Stefanie M. Hauck,Helmut Laumen,Wolfgang Wurst,Fernando Casares,José Luis Gómez-Skarmeta,Juliane Winkelmann +35 more
TL;DR: In vivo and in vitro analysis of a common SNP with small effect size showed allele-dependent function in the prospective basal ganglia representing the first neurodevelopmental region implicated in RLS.
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LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation
Christian B. Schiller,Kalliope N. Diakopoulos,Ina Rohwedder,Elisabeth Kremmer,Christine von Toerne,Marius Ueffing,Ulrich H. Weidle,Hiroshi Ohno,Elisabeth H. Weiss +8 more
TL;DR: It is reported that the transmembrane MHC class III protein leukocyte specific transcript 1 (LST1) induces the formation of functional nanotubes and is required for endogenous nanotube generation.
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The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation
Stefan J. Kempf,Arianna Casciati,Sonja Buratovic,Dirk Janik,Christine von Toerne,Marius Ueffing,Frauke Neff,Simone Moertl,Bo Stenerlöw,Anna Saran,Michael J. Atkinson,Per Eriksson,Simonetta Pazzaglia,Soile Tapio +13 more
TL;DR: These data suggest that neurocognitive disorders may be induced in adults when exposed at a young age to low and moderate cranial doses of radiation, which raises concerns about radiation safety standards and regulatory practices.