C
Christophe d'Enfert
Researcher at Pasteur Institute
Publications - 173
Citations - 17116
Christophe d'Enfert is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Candida albicans & Corpus albicans. The author has an hindex of 60, co-authored 173 publications receiving 14648 citations. Previous affiliations of Christophe d'Enfert include Centre national de la recherche scientifique & University of California, Berkeley.
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Journal ArticleDOI
Multilocus Sequence Typing Reveals Intrafamilial Transmission and Microevolutions of Candida albicans Isolates from the Human Digestive Tract
Marie-Elisabeth Bougnoux,Marie-Elisabeth Bougnoux,D. Diogo,Nadine François,Boualem Sendid,S. Veirmeire,Jean-Frederic Colombel,Christiane Bouchier,H. J. Van Kruiningen,Christophe d'Enfert,Daniel Poulain +10 more
TL;DR: This study was the first to jointly assess commensal carriage of C. albicans, intrafamilial transmission, and microevolution and suggests that the digestive tract provides an important and natural niche for microevolutions of diploid C.Albicans through the loss of heterozygosity.
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Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER.
TL;DR: Sar1p-Sec12p interaction may regulate the initiation of vesicle budding from the ER, and Sar1p binding to isolated membranes is enhanced at elevated levels of Sec12p.
Journal ArticleDOI
Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism.
Emilia Moreno-Ruiz,Marta Galán-Díez,Weidong Zhu,Elena Fernández-Ruiz,Christophe d'Enfert,Christophe d'Enfert,Scott G. Filler,Scott G. Filler,Pascale Cossart,Pascale Cossart,Pascale Cossart,Esteban Veiga +11 more
TL;DR: Data indicate that C.’albicans, like L. monocytogenes, hijacks the clathrin‐dependent endocytic machinery to invade host cells, and beads coated with Als3 were internalized in a clathin‐dependent manner.
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G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective.
TL;DR: Data indicate a striking diversity at the GPCR level, but little diversity of components at theG-protein and cAMP-signaling level, which may reflect the abilities of these fungi to adapt to various ecological niches and to integrate diverse environmental cues into highly conserved cellular processes.
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Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans.
Julie Bonhomme,Murielle Chauvel,Murielle Chauvel,Sophie Goyard,Sophie Goyard,Pascal Roux,Tristan Rossignol,Tristan Rossignol,Christophe d'Enfert,Christophe d'Enfert +9 more
TL;DR: The data indicate that a hypoxic environment is generated within C. albicans biofilms and that continued biofilm development requires a Tye7p‐dependent upregulation of glycolytic genes necessary to adapt to hypoxia and prevent uncontrolled hyphal formation.