Marta Galán-Díez

TL;DR: This study uncovers a bone-to-muscle feedforward endocrine axis that favors adaptation to exercise and can reverse the age-induced decline in exercise capacity.

TL;DR: Data indicate that C.’albicans, like L. monocytogenes, hijacks the clathrin‐dependent endocytic machinery to invade host cells, and beads coated with Als3 were internalized in a clathin‐dependent manner.

TL;DR: The results suggest that osteoblasts play a fundamental role in propagating leukemia in the marrow and may be a therapeutic target to induce hostility of the niche to leukemia blasts.

TL;DR: Whether noninvasive commensal microbes may possess previously unappreciated modes of antigen acquisition or communication with the host for maintenance of mucosal T cell homeostasis is explored.

TL;DR: It is demonstrated that a disruption of the C. albicans extracellular signal-regulated kinase (ERK)-like 1 (CEK1)-mediated MAPK pathway causes enhanced cell wall β-glucan exposure, triggering immune responses more efficiently than the wild type, thus establishing this fungal intracellular signaling route as a promising novel therapeutic target.