C
Christophe Ramière
Researcher at French Institute of Health and Medical Research
Publications - 22
Citations - 634
Christophe Ramière is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Population & Virus. The author has an hindex of 11, co-authored 19 publications receiving 518 citations. Previous affiliations of Christophe Ramière include Claude Bernard University Lyon 1 & University of Lyon.
Papers
More filters
Journal ArticleDOI
Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins
Vinca Icard,Olivier Diaz,Olivier Diaz,Caroline Scholtes,Laure Perrin-Cocon,Laure Perrin-Cocon,Christophe Ramière,Ralf Bartenschlager,François Penin,Vincent Lotteau,Patrice Andre +10 more
TL;DR: Data indicate that HCV envelope glycoproteins have the intrinsic capacity to utilize apoB synthesis and lipoprotein assembly machinery even in the absence of the other HCV proteins.
Journal ArticleDOI
Hepatitis E virus mutations associated with ribavirin treatment failure result in altered viral fitness and ribavirin sensitivity
Yannick Debing,Christophe Ramière,Kai Dallmeier,Géraldine Piorkowski,Mary-Anne Trabaud,Fanny Lebossé,Caroline Scholtes,Magali Roche,Catherine Legras-Lachuer,Xavier de Lamballerie,Patrice Andre,Johan Neyts +11 more
TL;DR: A patient with chronic hepatitis E experiencing ribavirin treatment failure with a completely resistant phenotype is presented and viral mutations associated with treatment failure are identified and investigated to investigate the underlying causes of treatment failure.
Journal ArticleDOI
Activity of Hexokinase Is Increased by Its Interaction with Hepatitis C Virus Protein NS5A
Christophe Ramière,Jonathan Rodriguez,Liviu S. Enache,Vincent Lotteau,Patrice Andre,Olivier Diaz +5 more
TL;DR: An increase in glucose consumption and lactate secretion in HCV-infected cells is observed, revealing higher glycolytic activity, and an interaction between the HCV NS5A nonstructural protein and cellular hexokinase 2, the first rate-limiting enzyme of gly colysis is identified.
Journal ArticleDOI
Hepatitis C virus spread from HIV-positive to HIV-negative men who have sex with men
Caroline Charre,Laurent Cotte,Rolf Kramer,Rolf Kramer,Patrick Miailhes,Matthieu Godinot,Joseph Koffi,Caroline Scholtes,Caroline Scholtes,Caroline Scholtes,Christophe Ramière,Christophe Ramière,Christophe Ramière +12 more
TL;DR: Recommendations for HCV surveillance should not be confined to HIV-positive MSM but should be extended toAIDS-negative MSM with similar risk factors, as it is suggested that several transmission events occurred within the study population.
Journal ArticleDOI
High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients
Caroline Scholtes,Caroline Scholtes,Christophe Ramière,Christophe Ramière,Dominique Rainteau,Laure Perrin-Cocon,Laure Perrin-Cocon,Claude Wolf,Lydie Humbert,Martine Carreras,Martine Carreras,Aurélie Guironnet-Paquet,Aurélie Guironnet-Paquet,Fabien Zoulim,Fabien Zoulim,Ralf Bartenschlager,Vincent Lotteau,Vincent Lotteau,Patrice Andre,Patrice Andre,Olivier Diaz,Olivier Diaz +21 more
TL;DR: LVPs are a mixed population of particles, comprising predominantly subviral particles that represent a distinct class of modified lipoproteins within the TRL family.