C
Christopher D. Breder
Researcher at Johns Hopkins University
Publications - 50
Citations - 6934
Christopher D. Breder is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Aripiprazole & Hypothalamus. The author has an hindex of 28, co-authored 50 publications receiving 6748 citations. Previous affiliations of Christopher D. Breder include Center for Drug Evaluation and Research & Food and Drug Administration.
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Interleukin-1 immunoreactive innervation of the human hypothalamus
TL;DR: Results indicate that IL-1 may be an intrinsic neuromodulator in central nervous system pathways that mediate various metabolic functions of the acute phase reaction, including the body temperature changes that produce the febrile response.
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Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.
Bo Xiao,Jian Cheng Tu,Ronald S. Petralia,Joseph P. Yuan,Andrew Doan,Christopher D. Breder,Alicia M. Ruggiero,Anthony Lanahan,Robert J. Wenthold,Paul F. Worley +9 more
TL;DR: Observations support a model in which the dynamic expression of Homer 1a competes with constitutively expressed CC-Homers to modify synaptic mGluR properties.
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Cloning and functional comparison of kappa and delta opioid receptors from mouse brain
TL;DR: RNA blotting studies and in situ hybridization histochemistry showed that kappa opioid receptor mRNA was expressed at high levels in brain in the neocortex, hippocampus, amygdala, medial habenula, hypothalamus, locus ceruleus, and parabrachial nucleus, suggesting that this receptor may play a role in arousal and regulation of autonomic and neuroendocrine functions.
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Characterization of inducible cyclooxygenase in rat brain
TL;DR: This study used Western blot analysis and immunohistochemistry to describe the biochemical characterization and anatomical distribution of the second, mitogen‐inducible form of this enzyme, COX 2 in the rat brain.
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Autonomic responses and efferent pathways from the insular cortex in the rat.
Yukihiko Yasui,Christopher D. Breder,Clifford B. Saper,Clifford B. Saper,David F. Cechetto,David F. Cechetto +5 more
TL;DR: The anatomical distribution of autonomic, particularly cardiovascular, responses originating in the insular cortex was examined by using systematic electrical microstimulation to demonstrate the localization of these responses to cell bodies in theinsular cortex.