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Ronald S. Petralia

Researcher at National Institutes of Health

Publications -  193
Citations -  23465

Ronald S. Petralia is an academic researcher from National Institutes of Health. The author has contributed to research in topics: AMPA receptor & Postsynaptic potential. The author has an hindex of 71, co-authored 188 publications receiving 22019 citations.

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Rapid Spine Delivery and Redistribution of AMPA Receptors After Synaptic NMDA Receptor Activation

TL;DR: Tetanic synaptic stimulation induced a rapid delivery of tagged receptors into dendritic spines as well as clusters in dendrites and may contribute to the enhanced AMPA receptor-mediated transmission observed during long-term potentiation and activity-dependent synaptic maturation.
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Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

TL;DR: Stargazer, an ataxic and epileptic mutant mouse, lacks functional AMPA receptors on cerebellar granule cells, and expression of a mutant stargazin lacking the PDZ-binding domain in hippocampal pyramidal cells disrupts synaptic AMPA receptor receptors, indicating that st argazin-like mechanisms for targeting AM PA receptors may be widespread in the central nervous system.
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Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins

TL;DR: It is reported that Shank proteins also bind to Homer, and Shank may cross-link Homer and PSD-95 complexes in the PSD and play a role in the signaling mechanisms of both mGluRs and NMDA receptors.
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Light and electron immunocytochemical localization of AMPA-selective glutamate receptors in the rat brain.

TL;DR: Staining was most prominent in forebrain structures such as the olfactory bulb and tubercle, septal nuclei, amygdaloid complex, hippocampus, induseum griseum, habenula, and interpeduncular nucleus, and in the cerebellum, with limited evidence of stained presynaptic terminals, excepting Bergmann glia.
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Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

TL;DR: Comparison with previous studies of localization of other glutamate receptor types revealed that NMDAR1 may colocalize with these other types in many neurons throughout the nervous system, implying that multiple types of NMDA receptors exist.